Gene

snai2

ID
ZDB-GENE-030326-6
Name
snail family zinc finger 2
Symbol
snai2 Nomenclature History
Previous Names
  • cb147 (1)
  • cb355 (1)
  • id:ibd5003
  • sb:cb355
  • sb:cb569
  • slug (1)
  • wu:fb83e12
  • wu:fd19g11
  • zgc:92564
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to localize to nuclear chromatin. Is expressed in several structures, including cardiovascular system; ectoderm; mesoderm; neural crest; and splanchnocranium. Human ortholog(s) of this gene implicated in Waardenburg syndrome type 2D and piebaldism. Orthologous to human SNAI2 (snail family transcriptional repressor 2).
Genome Resources
Note
None
Expression
All Expression Data
37 figures from 15 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Bickers et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With snai2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
piebaldism Alliance Piebaldism 172800
Waardenburg syndrome type 2D Alliance Waardenburg syndrome, type 2D 608890
Associated With snai2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013087 Zinc finger C2H2-type
Homologous_superfamily IPR036236 Zinc finger C2H2 superfamily
Domain Details Per Protein
Protein Length Zinc finger C2H2 superfamily Zinc finger C2H2-type
UniProtKB:Q5PQY5 257
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations