ZFIN ID: ZDB-GENE-030326-4
Gene Name: heat shock protein, alpha-crystallin-related, 1
Gene Symbol: hspb1

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Previous Names: hsp27 (1), cb153 (1), cb660 (1), id:ibd2821, sb:cb660, zgc:103437

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 39 figures from 11 publications
Directly Submitted Expression Data: 6 figures (12 images) from Thisse et al., 2001 [cb660]
  2 figures (2 images) from Kudoh et al., 2001 [ibd2821]
  6 figures (38 images) from Thisse et al., 2001 [cb153]
Wild-type Stages, Structures: Cleavage:16-cell (1.5h-1.75h) to Adult (90d-730d, breeding adult)
  adaxial cell, adductor mandibulae, atrioventricular canal, blastoderm (all 56) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents: MO1-hspb1 (1)
PHENOTYPE
Data: 4 figures from 2 publications
Observed in: adductor mandibulae muscle cell, adductor mandibulae regulation of myofibril size, adductor mandibulae, interhyoideus muscle cell (all 10) expand
DISEASE ASSOCIATED WITH hspb1 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Charcot-Marie-Tooth disease axonal type 2F Charcot-Marie-Tooth disease, axonal, type 2F 606595
Charcot-Marie-Tooth disease type 4 Neuropathy, distal hereditary motor, type IIB 608634
GENE ONTOLOGY
Ontology GO Term
Biological Process response to arsenic-containing substance (more)
Cellular Component cytoplasm (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001436 (1)
  • InterPro:IPR002068 (1)
  • InterPro:IPR008978 (1)
  • InterPro:IPR031107 (1)
  • PROSITE:PS01031 (1)
  • Pfam:PF00011 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA hspb1-001 (1) 1052
    ncRNA hspb1-002 (1) 745
    mRNA hspb1-003 (1) 498
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIES
    Ab1-hspb1 (1)
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM hspb1
    Tg(hspb1:EGFP), Tg(lyz:hspb1,mCherry), Tg2(hspb1:EGFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    hspb1Contained in: [Fosmid] ZFOS-631D6 (1)
    hspb1Contains: [STS] chunp30328
    hspb1Encodes: [EST] cb153 (1) (order this), cb660 (1) (order this), ibd2821 (order this)
    [cDNA] MGC:103437 (1) (order this), MGC:114088 (1) (order this), MGC:192174 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001008615 (1) 957bp
    Genomic GenBank:FP017189 (1) 33555bp
    Select Tool
    Polypeptide UniProtKB:A4VAK4 (1) 199aa
    Sequence Clusters UniGene:32244 (1)
    Sequence Information (all 36)
    OTHER hspb1 GENE PAGES
  • Gene:368243 (1)
  • VEGA:OTTDARG00000035270 (1)
  • Ensembl(GRCz10):ENSDARG00000041065 (1)
  • ORTHOLOGY for hspb1 (Chr: 5)
    Species Symbol Chromosome Accession # Evidence
    Human HSPB1 7
  • Gene:3315
  • OMIM:602195
  • HGNC:5246
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (34)