ZFIN ID: ZDB-GENE-030131-9770
Gene Name: angiomotin like 2a
Gene Symbol: amotl2a
Previous Names: amotl2, cb308 (1), sb:cb308, wu:fc41b07, wu:fc64c06
Location: Chr: 6 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 8 figures from 3 publications
Directly Submitted Expression Data: 6 figures (17 images) from Thisse et al., 2001 [cb308]
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Hatching:Long-pec (48.0h-60.0h)
  anterior axial hypoblast, artery, axial vasculature, blastomere (all 32) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fu45 Small Deletion Exon 3 Frameshift, Premature Stop TALEN
fu46 Small Deletion Exon 3 Frameshift, Premature Stop TALEN
sa16774 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18236 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18416 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa20712 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20713 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33875 Point Mutation Unknown Unknown ENU
    sa40700 Point Mutation Unknown Unknown ENU
    Targeting reagents: MO1-amotl2a (1), MO2-amotl2a (1), TALEN1-amotl2a (1)
    PHENOTYPE
    Data: 14 figures from 4 publications
    Observed in: angiogenesis, blood vessel, cell migration, convergent extension (all 32) expand
    DISEASE ASSOCIATED WITH amotl2a HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process dorsal aorta morphogenesis (more)
    Cellular Component cell cortex (more)
    Molecular Function protein binding (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR009114 (1)
  • InterPro:IPR024646 (1)
  • Pfam:PF12240 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA amotl2a-001 (1) 4147
    amotl2a-002 (1) 615
    amotl2a-003 (1) 557
    amotl2a-004 (1) 242
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM amotl2a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    amotl2aContained in: [BAC] DKEY-233G13 (1) (order this)
    amotl2aEncodes: [EST] cb308 (1) (order this), fc41b07, fc64c06
    [cDNA] MGC:194605 (1) (order this)
    amotl2aHas Artifact: [EST] fc41b02
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001080177 (1) 2434bp
    Genomic GenBank:CR626940 (1) 59073bp
    Select Tool
    Polypeptide UniProtKB:A1YB07 (1) 721aa
    Sequence Clusters UniGene:75364 (1)
    Sequence Information (all 19)
    OTHER amotl2a GENE PAGES
  • Gene:558920 (1)
  • VEGA:OTTDARG00000027218 (1)
  • Ensembl(GRCz10):ENSDARG00000061923 (1)
  • ORTHOLOGY for amotl2a (Chr: 6)
    Species Symbol Chromosome Accession # Evidence
    Human AMOTL2 3
  • Gene:51421
  • OMIM:614658
  • HGNC:17812
  • Amino acid sequence comparison (3)
    Conserved genome location (synteny) (2)
    Mouse Amotl2 9
  • MGI:1929286
  • Gene:56332
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (19)