Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030131-9770
Gene Name: angiomotin like 2a
Gene Symbol: amotl2a
Previous Names: amotl2, cb308 (1), sb:cb308, wu:fc41b07, wu:fc64c06
Location: Chr: 6   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 6 figures (17 images) from Thisse et al., 2001 [cb308]
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Hatching:Long-pec (48.0h-60.0h)
  anterior axial hypoblast, artery, axial vasculature, blastomere (all 32) expand
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa16774, sa18236, sa18416, sa20712, sa20713
Knockdown reagents: MO1-amotl2a (1), MO2-amotl2a (1)
PHENOTYPE
Data: 6 figures from 2 publications
Observed in: angiogenesis, blood vessel, cell migration, convergent extension (all 20) expand
GENE ONTOLOGY
Ontology GO Term
Biological Process establishment of localization in cell (more)
Cellular Component cell cortex (more)
Molecular Function protein binding (more)
GO Terms (all 13)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR009114 (1)
  • InterPro:IPR024646 (1)
  • Pfam:PF12240 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA amotl2a-001 (1) 4147
    amotl2a-002 (1) 615
    amotl2a-003 (1) 557
    amotl2a-004 (1) 242
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM amotl2a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    amotl2a Contained in: [BAC] DKEY-233G13 (1)
    amotl2a Encodes: [EST] cb308 (1) (order this), fc41b07, fc64c06
    [cDNA] MGC:194605 (1) (order this)
    amotl2a Has Artifact: [EST] fc41b02
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001080177 (1) 2434 bp
    Genomic GenBank:CR626940 (1) 59073 bp
    Select Tool
    Polypeptide UniProtKB:A1YB07 (1) 721 aa
    Sequence Clusters UniGene:75364 (1)
    Sequence Information (all 19)
    OTHER amotl2a GENE PAGES
  • Gene:558920 (1)
  • VEGA:OTTDARG00000027218 (1)
  • Ensembl(Zv9):ENSDARG00000061923 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish amotl2a 6  
    Human AMOTL2 3 (3q21-q22)
  • OMIM:614658
  • Gene:51421
  • Mouse Amotl2 9 ( 54.71 cM)
  • MGI:1929286
  • Gene:56332
  • Orthology Details
    CITATIONS (17)