ZFIN ID: ZDB-GENE-030131-9770
Gene Name: angiomotin like 2a
Gene Symbol: amotl2a
Previous Names: amotl2, cb308 (1), sb:cb308, wu:fc41b07, wu:fc64c06
Location: Chr: 6 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 8 figures from 3 publications
Directly Submitted Expression Data: 6 figures (17 images) from Thisse et al., 2001 [cb308]
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Hatching:Long-pec (48.0h-60.0h)
  anterior axial hypoblast, artery, axial vasculature, blastomere (all 32) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
fu45 Small Deletion TALEN
fu46 Small Deletion TALEN
sa16774 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa18236 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa18416 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa20712 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa20713 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-amotl2a (1), MO2-amotl2a (1), TALEN1-amotl2a (1)
    PHENOTYPE
    Data: 14 figures from 4 publications
    Observed in: angiogenesis, blood vessel, cell migration, convergent extension (all 32) expand
    DISEASE ASSOCIATED WITH amotl2a HUMAN ORTHOLOG No data available
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process dorsal aorta morphogenesis (more)
    Cellular Component cell cortex (more)
    Molecular Function protein binding (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR009114 (1)
  • InterPro:IPR024646 (1)
  • Pfam:PF12240 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA amotl2a-001 (1) 4147
    amotl2a-002 (1) 615
    amotl2a-003 (1) 557
    amotl2a-004 (1) 242
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM amotl2a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    amotl2aContained in: [BAC] DKEY-233G13 (1) (order this)
    amotl2aEncodes: [EST] cb308 (1) (order this), fc41b07, fc64c06
    [cDNA] MGC:194605 (1) (order this)
    amotl2aHas Artifact: [EST] fc41b02
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001080177 (1) 2434bp
    Genomic GenBank:CR626940 (1) 59073bp
    Select Tool
    Polypeptide UniProtKB:A1YB07 (1) 721aa
    Sequence Clusters UniGene:75364 (1)
    Sequence Information (all 19)
    OTHER amotl2a GENE PAGES 
  • Gene:558920 (1)
  • VEGA:OTTDARG00000027218 (1)
  • Ensembl(GRCz10):ENSDARG00000061923 (1)
  • ORTHOLOGY for amotl2a (Chr: 6) 
    Species Symbol Chromosome Accession # Evidence
    Human AMOTL2 3
  • Gene:51421
  • OMIM:614658
  • HGNC:17812
  • Amino acid sequence comparison (3)
    Conserved genome location (synteny) (2)
    Mouse Amotl2 9
  • MGI:1929286
  • Gene:56332
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (19)