Gene

hmcn2

ID
ZDB-GENE-030131-9765
Name
hemicentin 2
Symbol
hmcn2 Nomenclature History
Previous Names
  • cb30 (1)
  • sb:cb30 (1)
  • si:ch211-204c5.1
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have calcium ion binding activity. Involved in several processes, including embryonic medial fin morphogenesis; mesenchymal cell migration; and skin morphogenesis. Predicted to localize to extracellular region. Is expressed in several structures, including axis; median fin fold; mesoderm; myotome; and trunk. Orthologous to human HMCN2 (hemicentin 2).
Genome Resources
Note
None
Expression
All Expression Data
13 figures from 6 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hmcn2 Human Ortholog
No data available
Associated With hmcn2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018097 EGF-like calcium-binding, conserved site
Domain IPR000742 EGF-like domain
Domain IPR001881 EGF-like calcium-binding domain
Domain IPR003598 Immunoglobulin subtype 2
Domain IPR003599 Immunoglobulin subtype
Domain IPR006605 G2 nidogen/fibulin G2F
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013098 Immunoglobulin I-set
Domain IPR013106 Immunoglobulin V-set domain
Domain IPR026823 Complement Clr-like EGF domain
Family IPR032984 Hemicentin-2
Homologous_superfamily IPR009017 Green fluorescent protein
Homologous_superfamily IPR009030 Growth factor receptor cysteine-rich domain superfamily
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Homologous_superfamily IPR036383 Thrombospondin type-1 (TSP1) repeat superfamily
Homologous_superfamily IPR036465 von Willebrand factor A-like domain superfamily
PTM IPR000152 EGF-type aspartate/asparagine hydroxylation site
Repeat IPR000884 Thrombospondin type-1 (TSP1) repeat
Domain Details Per Protein
Protein Length Complement Clr-like EGF domain EGF-like calcium-binding, conserved site EGF-like calcium-binding domain EGF-like domain EGF-type aspartate/asparagine hydroxylation site G2 nidogen/fibulin G2F Green fluorescent protein Growth factor receptor cysteine-rich domain superfamily Hemicentin-2 Immunoglobulin I-set Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin subtype Immunoglobulin subtype 2 Immunoglobulin V-set domain Thrombospondin type-1 (TSP1) repeat Thrombospondin type-1 (TSP1) repeat superfamily von Willebrand factor A-like domain superfamily
UniProtKB:E7EY71 1126
UniProtKB:D7PS98 424
UniProtKB:F1R2Y2 293
UniProtKB:M9MMB9 815
UniProtKB:F1R747 158
UniProtKB:F1QYL6 89
UniProtKB:D7PS97 10
UniProtKB:E7F3V2 4212
UniProtKB:F1Q9T8 122
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-hmcn2 polyclonal Rabbit
  • IHC
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Citations