ZFIN ID: ZDB-GENE-030131-9732
Gene Name: apolipoprotein Bb, tandem duplicate 1
Gene Symbol: apobb.1    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: apobb, apobl (1), cb235 (1), hm:zeh1207, sb:cb235, si:ch211-219i10.1, wu:fb39c11, wu:fc51e12, zeh1207

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have lipid transporter activity. Involved in cellular response to xenobiotic stimulus. Is expressed in intestine; liver; and yolk syncytial layer. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); biliary tract cancer (multiple); familial hyperlipidemia (multiple); hypobetalipoproteinemia (multiple); and sickle cell anemia. Orthologous to human APOB (apolipoprotein B).
Genome Resources: Alliance (1),  Gene:321166 (1),  Ensembl(GRCz11):ENSDARG00000022767 (2)
GENE EXPRESSION
All Expression Data: 19 figures from 7 publications
Directly Submitted Expression Data: 6 figures (6 images) from Thisse et al., 2001 [cb235]
  6 figures (6 images) from Thisse et al., 2004 [IMAGE:7138028]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
c832Tg Transgenic Insertion Unknown Unknown DNA_AND_TALEN
sa6637 Point Mutation Unknown Premature Stop ENU
sa6638 Point Mutation Unknown Premature Stop ENU
sa10039 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12118 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16833 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18137 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32301 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37070 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37071 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43475 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43476 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-apobb.1 N/A 2
    MO2-apobb.1 N/A 2
    TALEN1-apobb.1 1
    DISEASE ASSOCIATED WITH apobb.1 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    familial hypobetalipoproteinemia 1 Alliance Hypobetalipoproteinemia 615558
    Hypercholesterolemia, familial, 2 144010
    DISEASE ASSOCIATED WITH apobb.1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular response to xenobiotic stimulus (more)
    Cellular Component low-density lipoprotein particle (more)
    Molecular Function lipid transporter activity (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA apobb.1-201 (1)    Ensembl 11495
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM apobb.1 No data available
    MARKER RELATIONSHIPS
    apobb.1 Contained in: [BAC] CH211-219I10 (1)
    apobb.1 Encodes: [EST] cb235 (1) (order this), fb39c11 (1), fc51e12 (1), IMAGE:7050742, IMAGE:7138028 (1), fb39e09 (1), zeh1207 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001030062 (1) 11495 nt
    Genomic GenBank:BX511210 (1) 62936 nt
    Select Tool
    Polypeptide UniProtKB:Q5TZ29 (1) 3730 aa
    Sequence Information (all 26)
    ORTHOLOGY for apobb.1 ( Chr: 20 )
    CITATIONS (50)