Gene

apobb.1

ID
ZDB-GENE-030131-9732
Name
apolipoprotein Bb, tandem duplicate 1
Symbol
apobb.1 Nomenclature History
Previous Names
  • apobb
  • apobl (1)
  • cb235 (1)
  • hm:zeh1207
  • sb:cb235
  • si:ch211-219i10.1
  • wu:fb39c11
  • wu:fc51e12
  • zeh1207
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have lipid transporter activity. Involved in cellular response to xenobiotic stimulus. Is expressed in intestine; liver; and yolk syncytial layer. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); biliary tract cancer (multiple); familial hyperlipidemia (multiple); hypobetalipoproteinemia (multiple); and sickle cell anemia. Orthologous to human APOB (apolipoprotein B).
Genome Resources
Note
None
Expression
All Expression Data
19 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
Fig. 7 from Seth et al., 2010
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With apobb.1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
familial hypobetalipoproteinemia 1 Alliance Hypobetalipoproteinemia 615558
Hypercholesterolemia, familial, 2 144010
Associated With apobb.1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001747 Lipid transport protein, N-terminal
Domain IPR009454 Lipid transport, open beta-sheet
Domain IPR015255 Vitellinogen, open beta-sheet
Homologous_superfamily IPR011030 Lipovitellin-phosvitin complex, superhelical domain
Homologous_superfamily IPR015816 Vitellinogen, beta-sheet N-terminal
Homologous_superfamily IPR015819 Lipid transport protein, beta-sheet shell
Homologous_superfamily IPR016024 Armadillo-type fold
Domain Details Per Protein
Protein Length Armadillo-type fold Lipid transport, open beta-sheet Lipid transport protein, beta-sheet shell Lipid transport protein, N-terminal Lipovitellin-phosvitin complex, superhelical domain Vitellinogen, beta-sheet N-terminal Vitellinogen, open beta-sheet
UniProtKB:A0A286YAF6 3643
UniProtKB:A8E4Z5 419
UniProtKB:Q5TZ29 3730
UniProtKB:Q5BLC2 461
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations