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ZIRC
ZFIN ID: ZDB-GENE-030131-9732
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Gene Name: apolipoprotein Bb, tandem duplicate 1
Gene Symbol: apobb.1
Sequence Ontology ID : SO:0001217

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Previous Names: apobb, apobl (1), cb235 (1), hm:zeh1207, sb:cb235, si:ch211-219i10.1, wu:fb39c11, wu:fc51e12, zeh1207

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(Including Attributions)
Location: Chr: 20 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have lipid transporter activity. Involved in cellular response to xenobiotic stimulus. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple);  ...
GENE EXPRESSION
All Expression Data: 19 figures from 7 publications
Directly Submitted Expression Data: 6 figures (6 images) from Thisse et al., 2001 [cb235]
  6 figures (6 images) from Thisse et al., 2004 [IMAGE:7138028]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6637 Point Mutation Unknown Premature Stop ENU
sa6638 Point Mutation Unknown Premature Stop ENU
sa10039 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa12118 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa16833 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa18137 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa32301 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa37070 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa37071 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa43475 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa43476 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • Targeting reagents:
    PHENOTYPE
    Data: Fig. 7 from Seth et al., 2010
    Observed in:
    DISEASE ASSOCIATED WITH apobb.1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    familial hypobetalipoproteinemia 1 Hypobetalipoproteinemia 615558
    Hypercholesterolemia, familial, 2 144010
    DISEASE ASSOCIATED WITH apobb.1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular response to xenobiotic stimulus (more)
    Molecular Function lipid transporter activity (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001747 (1)
  • InterPro:IPR009454 (1)
  • InterPro:IPR011030 (1)
  • InterPro:IPR015255 (1)
  • InterPro:IPR015816 (1)
  • InterPro:IPR015819 (1)
  • InterPro:IPR016024 (1)
  • PROSITE:PS51211 (1)
  • Pfam:PF01347 (1)
  • Pfam:PF06448 (1)
  • Pfam:PF09172 (1)
    • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA apobb.1-201 (1) 11495
    Select Tool
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM apobb.1 No data available
    MARKER RELATIONSHIPS
    apobb.1 Contained in: [BAC] CH211-219I10 (1) (order this)
    apobb.1 Encodes: [EST] cb235 (1) (order this), fb39c11 (1), fc51e12 (1), IMAGE:7050742, IMAGE:7138028 (1) (order this), fb39e09 (1), zeh1207 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001030062 (1) 11495 bp
    Select Tool
    Genomic GenBank:BX511210 (1) 62936 bp
    Select Tool
    Polypeptide UniProtKB:Q5TZ29 (1) 3730 aa
    Select Tool
    Sequence Clusters UniGene:76570 (1)
    Sequence Information (all 27)
    OTHER apobb.1 GENE PAGES
  • Alliance (1)
  • Gene:321166 (1)
  • VEGA:OTTDARG00000005612 (1)
  • Ensembl(GRCz11):ENSDARG00000022767 (2)
    • ORTHOLOGY for apobb.1 ( Chr: 20 )
    CITATIONS (48)