ZFIN ID: ZDB-GENE-030131-9710
Gene Name: Yes-associated protein 1
Gene Symbol: yap1
Sequence Ontology ID : SO:0000704

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Previous Names: yap (1), cb194 (1), sb:cb194, si:ch211-181p1.5 (1), si:dkey-3b8.3, wu:fc18c04, zgc:158380

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(Including Attributions)
Location: Chr: 18 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Involved in several processes, including animal organ development, blood vessel morphogenesis, and cilium assembly; localizes to the chromatin and nucleus; used to study coloboma; orthologous to  ...
GENE EXPRESSION
All Expression Data: 18 figures from 9 publications
Directly Submitted Expression Data: 6 figures (12 images) from Thisse et al., 2001 [cb194]
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
bns19 Small Deletion Exon 1 Frameshift, Premature Stop CRISPR
fu47 Small Deletion Exon 2 Frameshift, Premature Stop TALEN
fu48 Small Deletion Exon 2 Frameshift, Premature Stop TALEN
la013286Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la020426Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • mw48 Small Deletion Unknown Frameshift, Premature Stop TALEN
    mw69 Small Deletion Unknown Unknown TALEN
    ncv101 Small Deletion Exon 1 Premature Stop TALEN
    ncv117 Small Deletion Exon 1 Frameshift, Premature Stop TALEN
    nl13 Point Mutation Acceptor Splice Site of Intron 4 Unknown ENU
    sa23348 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23349 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • swu45 Small Deletion Exon 1 Frameshift, Premature Stop TALEN
    Targeting reagents:
    PHENOTYPE
    Data: 39 figures from 15 publications
    Observed in:
    DISEASE ASSOCIATED WITH yap1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Coloboma, ocular, with or without hearing impairment, cleft lip/palate, and/or mental retardation 120433
    DISEASE ASSOCIATED WITH yap1 VIA EXPERIMENTAL MODELS
    Human Disease Fish Conditions Citations
    coloboma yap1nl13/nl13 standard conditions Miesfeld et al., 2015
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process BMP signaling pathway (more)
    Cellular Component chromatin (more)
    Molecular Function protein binding (more)
    GO Terms (all 27)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA yap1-201 (1) 3940
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM yap1
    MARKER RELATIONSHIPS
    yap1Contained in: [BAC] DKEY-3B8 (1) (order this)
    yap1Encodes: [EST] cb194 (1) (order this), fc18c04 (1)
    [cDNA] MGC:158380 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001139480 (1)
    Genomic GenBank:AL954841 (1) 149277bp
    Select Tool
    Polypeptide UniProtKB:Q1L8J7 (1) 442aa
    Sequence Clusters UniGene:119226 (1)
    Sequence Information (all 21)
    OTHER yap1 GENE PAGES
  • Alliance (1)
  • Gene:561411 (1)
  • VEGA:OTTDARG00000013411 (1)
  • ORTHOLOGY for yap1 (Chr: 18)
    CITATIONS (54)