ZFIN ID: ZDB-GENE-030131-9511
Gene Name: ddb1 and cul4 associated factor 7
Gene Symbol: dcaf7    Nomenclature History

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Previous Names: AN11 homolog (1), dirty south, dys, fj83g06, han11l (1), wdr68, wu:fj83g06, zgc:63940

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Involved in cartilage development and embryonic viscerocranium morphogenesis. Localizes to nucleus. Is expressed in forebrain; head; hindbrain; and somite. Orthologous to human DCAF7 (DDB1 and CUL4 associated factor 7).
Genome Resources: Alliance (1),  Gene:337565 (1),  Ensembl(GRCz11):ENSDARG00000054355 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:63940]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi3812Tg Transgenic Insertion Exon 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la010737Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14350 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33209 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-dcaf7 N/A 4
    MO2-dcaf7 N/A 3
    DISEASE ASSOCIATED WITH dcaf7 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dcaf7 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cartilage development (more)
    Cellular Component nucleus (more)
    Molecular Function protein binding (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dcaf7-201 (1)    Ensembl 2496
    ncRNA dcaf7-002 (1)    Ensembl 1040
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dcaf7
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(hsp70l:GFP-dcaf7,myl7:EGFP) hsp70lmyl7 dcaf7EGFPGFP Danio rerio 2 1
    MARKER RELATIONSHIPS
    dcaf7 Contained in: [BAC] DKEY-194J22 (1) (order this)
    dcaf7 Encodes: [EST] fj83g06
    [cDNA] MGC:63940 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200069 (1) 2289 nt
    Genomic GenBank:CU062431 (1) 183293 nt
    Select Tool
    Polypeptide UniProtKB:Q7T3E0 (1) 342 aa
    Sequence Information (all 12)
    ORTHOLOGY for dcaf7 ( Chr: 3 )
    CITATIONS (37)