ZFIN ID: ZDB-GENE-030131-9446
Gene Name: salt-inducible kinase 1
Gene Symbol: sik1    Nomenclature History

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Previous Names: fj78h07, si:ch211-235e18.3, wu:fj78h07

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and protein phosphorylation. Predicted to localize to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 30. Orthologous to several human genes including SIK1B (salt inducible kinase 1B (putative)).
Genome Resources: Alliance (1),  Gene:553465 (1),  Ensembl(GRCz11):ENSDARG00000058606 (2)
GENE EXPRESSION
All Expression Data: Fig. 1 from Klangnurak et al., 2018
High Throughput Expression: GEO (1) Expression Atlas (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH sik1 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
early infantile epileptic encephalopathy 30 Alliance Epileptic encephalopathy, early infantile, 30 616341
DISEASE ASSOCIATED WITH sik1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process protein phosphorylation (more)
Cellular Component cytoplasm (more)
Molecular Function ATP binding (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA sik1-201 (1)    Ensembl 4880
ncRNA sik1-002 (1)    Ensembl 539
sik1-003 (1)    Ensembl 606
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM sik1 No data available
MARKER RELATIONSHIPS
sik1 Contained in: [BAC] CH211-235E18 (1)
sik1 Encodes: [EST] fj78h07
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001126383 (1) 4880 nt
Genomic GenBank:BX537313 (1) 196642 nt
Select Tool
Polypeptide UniProtKB:B0S6K0 (1) 811 aa
Sequence Information (all 18)
ORTHOLOGY for sik1 ( Chr: 9 )
CITATIONS (18)