Gene

arhgef9b

ID
ZDB-GENE-030131-7745
Name
Cdc42 guanine nucleotide exchange factor (GEF) 9b
Symbol
arhgef9b Nomenclature History
Previous Names
  • arhgef9
  • wu:fj33b10
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have guanyl-nucleotide exchange factor activity. Involved in filopodium assembly and sprouting angiogenesis. Predicted to localize to cytoplasm and postsynaptic density. Is expressed in caudal artery; caudal vein plexus; dorsal aorta; and intersegmental vessel. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 8. Orthologous to human ARHGEF9 (Cdc42 guanine nucleotide exchange factor 9).
Genome Resources
Note
None
Expression
All Expression Data
1 figure from Wakayama et al., 2015
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Wakayama et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With arhgef9b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
developmental and epileptic encephalopathy 8 Alliance Developmental and epileptic encephalopathy 8 300607
Associated With arhgef9b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000219 Dbl homology (DH) domain
Domain IPR001452 SH3 domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR035728 Rho guanine nucleotide exchange factor 9, SH3 domain
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR035899 Dbl homology (DH) domain superfamily
Homologous_superfamily IPR036028 SH3-like domain superfamily
Domain Details Per Protein
Protein Length Dbl homology (DH) domain Dbl homology (DH) domain superfamily PH-like domain superfamily Pleckstrin homology domain Rho guanine nucleotide exchange factor 9, SH3 domain SH3 domain SH3-like domain superfamily
UniProtKB:A0A2R8QB69 485
UniProtKB:A0A2R8QKQ0 468
UniProtKB:A0A2R8QGA7 509
UniProtKB:A0A2R8RV69 464
UniProtKB:A0A2R8QCR3 418
UniProtKB:F1Q628 514
UniProtKB:A0A2R8RVC8 480
UniProtKB:A0A2R8QEM2 530
UniProtKB:A0A2R8Q858 461
UniProtKB:A0A2R8Q3X9 546
UniProtKB:C1J0C6 236
UniProtKB:A0A2R8QCF3 550
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations