Gene

kat8

ID
ZDB-GENE-030131-7510
Name
K(lysine) acetyltransferase 8
Symbol
kat8 Nomenclature History
Previous Names
  • myst1
  • wu:fb22g02
  • wu:fj22d09
  • zgc:66387
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have histone acetyltransferase activity (H4-K16 specific); histone binding activity; and transcription coregulator activity. Involved in primitive hemopoiesis. Predicted to localize to MSL complex and nuclear chromatin. Orthologous to human KAT8 (lysine acetyltransferase 8).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
Fig. 2 from Huang et al., 2013
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kat8 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Li-Ghorgani-Weisz-Hubshman syndrome 618974
Associated With kat8 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000953 Chromo/chromo shadow domain
Domain IPR002717 Histone acetyltransferase domain, MYST-type
Domain IPR025995 RNA binding activity-knot of a chromodomain
Domain IPR040706 MYST, zinc finger domain
Family IPR037906 Histone acetyltransferase KAT8
Homologous_superfamily IPR016181 Acyl-CoA N-acyltransferase
Homologous_superfamily IPR016197 Chromo-like domain superfamily
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Acyl-CoA N-acyltransferase Chromo/chromo shadow domain Chromo-like domain superfamily Histone acetyltransferase domain, MYST-type Histone acetyltransferase KAT8 MYST, zinc finger domain RNA binding activity-knot of a chromodomain Winged helix-like DNA-binding domain superfamily
UniProtKB:Q7SXF3 487
UniProtKB:A0A0R4IZD0 531
UniProtKB:A0A2R8RHP9 545
UniProtKB:A0A2R8QAY9 498
UniProtKB:A9JTB7 487
UniProtKB:F1QX50 502
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations