Gene

kat8

ID
ZDB-GENE-030131-7510
Name
K(lysine) acetyltransferase 8
Symbol
kat8 Nomenclature History
Previous Names
  • myst1
  • wu:fb22g02
  • wu:fj22d09
  • zgc:66387
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have histone acetyltransferase activity (H4-K16 specific); histone binding activity; and transcription coregulator activity. Involved in primitive hemopoiesis. Predicted to localize to MSL complex. Orthologous to human KAT8 (lysine acetyltransferase 8).
Genome Resources
Note
None
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Huang et al., 2013
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kat8 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Li-Ghorgani-Weisz-Hubshman syndrome 618974
Associated With kat8 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000953 Chromo/chromo shadow domain
Domain IPR002717 Histone acetyltransferase domain, MYST-type
Domain IPR025995 RNA binding activity-knot of a chromodomain
Domain IPR040706 MYST, zinc finger domain
Family IPR037906 Histone acetyltransferase KAT8
Homologous_superfamily IPR016181 Acyl-CoA N-acyltransferase
Homologous_superfamily IPR016197 Chromo-like domain superfamily
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Acyl-CoA N-acyltransferase Chromo/chromo shadow domain Chromo-like domain superfamily Histone acetyltransferase domain, MYST-type Histone acetyltransferase KAT8 MYST, zinc finger domain RNA binding activity-knot of a chromodomain Winged helix-like DNA-binding domain superfamily
UniProtKB:A0A0R4IZD0 531
UniProtKB:A9JTB7 487
UniProtKB:F1QX50 502
UniProtKB:Q7SXF3 487
UniProtKB:A0A2R8RHP9 545
UniProtKB:A0A2R8QAY9 498
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations