ZFIN ID: ZDB-GENE-030131-7435
Gene Name: poly (ADP-ribose) polymerase family, member 3
Gene Symbol: parp3    Nomenclature History

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Previous Names: fj17c06, wu:fj17c06, zgc:66157 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have NAD+ ADP-ribosyltransferase activity and protein ADP-ribosylase activity. Involved in ectodermal placode development and regulation of neural crest formation. Predicted to localize to nucleolus and site of double-strand break. Is expressed in axis and notochord. Orthologous to human PARP3 (poly(ADP-ribose) polymerase family member 3).
Genome Resources: Alliance (1),  Gene:335495 (1),  Ensembl(GRCz11):ENSDARG00000003961 (2)
GENE EXPRESSION
All Expression Data: 8 figures from 3 publications
Directly Submitted Expression Data: 6 figures (7 images) from Thisse et al., 2004 [MGC:66157]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa8845 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa26806 Point Mutation Unknown Splice Site ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-parp3 N/A 1
    MO2-parp3 N/A 1
    MO3-parp3 N/A 1
    DISEASE ASSOCIATED WITH parp3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH parp3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process ectodermal placode development (more)
    Cellular Component nucleolus (more)
    Molecular Function NAD+ ADP-ribosyltransferase activity (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA parp3-201 (1)    Ensembl 2456
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-parp3 polyclonal Rabbit WB Enzo Life Sciences International, Inc.
    1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM parp3 No data available
    MARKER RELATIONSHIPS
    parp3 Contained in: [BAC] DKEYP-111E5 (1)
    parp3 Encodes: [EST] fj17c06
    [cDNA] MGC:56135 (1), MGC:66157 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200501 (1) 2473 nt
    Genomic GenBank:BX664752 (1) 156503 nt
    Select Tool
    Polypeptide UniProtKB:F1QSK1 (1) 531 aa
    Sequence Information (all 14)
    ORTHOLOGY for parp3 ( Chr: 6 )
    CITATIONS (27)