Gene

parp3

ID
ZDB-GENE-030131-7435
Name
poly (ADP-ribose) polymerase family, member 3
Symbol
parp3 Nomenclature History
Previous Names
  • fj17c06
  • wu:fj17c06
  • zgc:66157 (1)
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have NAD+ ADP-ribosyltransferase activity and protein ADP-ribosylase activity. Involved in ectodermal placode development and regulation of neural crest formation. Predicted to localize to nucleolus and site of double-strand break. Is expressed in axis and notochord. Orthologous to human PARP3 (poly(ADP-ribose) polymerase family member 3).
Genome Resources
Note
None
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from Rouleau et al., 2011
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With parp3 Human Ortholog
No data available
Associated With parp3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004102 Poly(ADP-ribose) polymerase, regulatory domain
Domain IPR008893 WGR domain
Domain IPR012317 Poly(ADP-ribose) polymerase, catalytic domain
Family IPR031275 Protein mono-ADP-ribosyltransferase PARP3
Homologous_superfamily IPR036616 Poly(ADP-ribose) polymerase, regulatory domain superfamily
Homologous_superfamily IPR036930 WGR domain superfamily
Domain Details Per Protein
Protein Length Poly(ADP-ribose) polymerase, catalytic domain Poly(ADP-ribose) polymerase, regulatory domain Poly(ADP-ribose) polymerase, regulatory domain superfamily Protein mono-ADP-ribosyltransferase PARP3 WGR domain WGR domain superfamily
UniProtKB:F1QSK1 531
UniProtKB:Q7ZVB0 531
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-parp3 polyclonal Rabbit
  • WB
Enzo Life Sciences International, Inc.
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations