ZFIN ID: ZDB-GENE-030131-73
Gene Name: transforming growth factor, beta-induced
Gene Symbol: tgfbi
Sequence Ontology ID : SO:0000704

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Previous Names: big-h3 (1), etID38199.14 (1), hm:zeh0933, wu:fa13f05 (1), zgc:110495

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(Including Attributions)
Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have cell adhesion molecule binding activity; involved in cellular response to xenobiotic stimulus and muscle fiber development; predicted to localize to the extracellular matrix and  ...
GENE EXPRESSION
All Expression Data: 16 figures from 9 publications
Directly Submitted Expression Data: 6 figures (23 images) from Thisse et al., 2004 [IMAGE:6903641]
Wild-type Stages, Structures: Gastrula:Bud (10.0h-10.33h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la018916Tg Transgenic Insertion Unknown Unknown DNA
la018917Tg Transgenic Insertion Unknown Unknown DNA
sa22487 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39002 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42397 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 3 figures from Kim et al., 2009
    Observed in:
    DISEASE ASSOCIATED WITH tgfbi HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    epithelial basement membrane dystrophy Corneal dystrophy, epithelial basement membrane 121820
    granular corneal dystrophy type II Corneal dystrophy, Avellino type 607541
    lattice corneal dystrophy Corneal dystrophy, lattice type I 122200
    Reis-Bucklers corneal dystrophy Corneal dystrophy, Reis-Bucklers type 608470
    Thiel-Behnke corneal dystrophy Corneal dystrophy, Thiel-Behnke type 602082
    Corneal dystrophy, lattice type IIIA 608471
    Corneal dystrophy, Groenouw type I 121900
    DISEASE ASSOCIATED WITH tgfbi VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular response to xenobiotic stimulus (more)
    Cellular Component extracellular space (more)
    Molecular Function collagen binding (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000782 (1)
  • InterPro:IPR011489 (1)
  • InterPro:IPR016666 (1)
  • InterPro:IPR032954 (1)
  • InterPro:IPR036378 (1)
  • PROSITE:PS50213 (1)
  • PROSITE:PS51041 (1)
  • Pfam:PF02469 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tgfbi-001 (1) 3037
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tgfbi No data available
    MARKER RELATIONSHIPS
    tgfbiContained in: [BAC] DKEYP-110E4 (1)
    tgfbiContains: [SNP] rs3728631 (1), rs3728642 (1), rs3728643 (1), rs3728644 (1), rs3728645 (1)
    tgfbiEncodes: [EST] fa13f05 (1), IMAGE:6903641 (1) (order this), zeh0933
    [cDNA] MGC:110495 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_182862 (1) 3046bp
    Genomic GenBank:BX323077 (1) 195732bp
    Select Tool
    Polypeptide UniProtKB:A0A0B5JSG0 (1) 677aa
    Sequence Clusters UniGene:742 (1)
    Sequence Information (all 23)
    OTHER tgfbi GENE PAGES
  • Alliance (1)
  • Gene:321421 (1)
  • VEGA:OTTDARG00000016647 (1)
  • Ensembl(GRCz11):ENSDARG00000071586 (2)
  • ORTHOLOGY for tgfbi (Chr: 14)
    CITATIONS (41)