ZFIN ID: ZDB-GENE-030131-7145
Gene Name: collagen, type XVII, alpha 1b
Gene Symbol: col17a1b    Nomenclature History

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Previous Names: col17a1 (1), col17a1a, fk89a06, si:ch211-223p8.6, wu:fk89a06 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have extracellular matrix structural constituent. Involved in lateral line system development. Predicted to localize to extracellular matrix and extracellular space. Is expressed in hypodermis; lateral line; and neuromast. Human ortholog(s) of this gene implicated in epithelial recurrent erosion dystrophy; junctional epidermolysis bullosa; and junctional epidermolysis bullosa non-Herlitz type. Orthologous to human COL17A1 (collagen type XVII alpha 1 chain).
Genome Resources: Alliance (1),  Gene:568794 (1),  Ensembl(GRCz11):ENSDARG00000079011 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6300 Point Mutation Unknown Splice Site ENU
sa18664 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22298 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22299 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31930 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-col17a1b N/A 2
    DISEASE ASSOCIATED WITH col17a1b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    epithelial recurrent erosion dystrophy Alliance Epithelial recurrent erosion dystrophy 122400
    junctional epidermolysis bullosa non-Herlitz type Alliance Epidermolysis bullosa, junctional, localisata variant 226650
    Epidermolysis bullosa, junctional, non-Herlitz type 226650
    DISEASE ASSOCIATED WITH col17a1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process lateral line system development (more)
    Cellular Component integral component of membrane (more)
    Molecular Function extracellular matrix structural constituent (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA col17a1b-202 (1)    Ensembl 4533
    col17a1b-203 (1)    Ensembl 510
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM col17a1b No data available
    MARKER RELATIONSHIPS
    col17a1b Contained in: [BAC] CH211-223P8 (1)
    col17a1b Encodes: [EST] fk89a06
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_005156931 (1)
    Genomic GenBank:AL929005 (1) 166364 nt
    Select Tool
    Polypeptide UniProtKB:F1R619 (1) 1368 aa
    Sequence Information (all 24)
    ORTHOLOGY for col17a1b ( Chr: 13 )
    CITATIONS (22)