header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030131-7116
Gene Name: paraoxonase 2
Gene Symbol: pon2
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: fk84f07, wu:fk84f07, zgc:77556

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 16 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have arylesterase activity. Human ortholog(s) of this gene implicated in artery disease (multiple); neurodegenerative disease (multiple); type 2 diabetes mellitus; and vascular dementia.  ...
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Directly Submitted Expression Data: 1 figure (2 images) from Thisse et al., 2004 [MGC:77556]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:6911665]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Days 14-20 (14d-21d, 6.2mm, 10 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fh450 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36123 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pon2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    {Coronary artery disease, susceptibility to}
    DISEASE ASSOCIATED WITH pon2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to toxic substance (more)
    Cellular Component cellular_component (more)
    Molecular Function arylesterase activity (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002640 (1)
  • InterPro:IPR011042 (1)
  • InterPro:IPR011045 (1)
  • Pfam:PF01731 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA pon2-002 (1) 853
    mRNA pon2-201 (1) 1169
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM pon2 No data available
    MARKER RELATIONSHIPS
    pon2Contained in: [BAC] DKEY-56F14 (1) (order this)
    pon2Encodes: [EST] fk84f07, IMAGE:6911665 (1) (order this)
    [cDNA] MGC:77556 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212734 (1) 1220bp
    Genomic GenBank:CR848666 (1) 106065bp
    Select Tool
    Polypeptide UniProtKB:Q6NXA5 (1) 355aa
    Sequence Clusters UniGene:82081 (1)
    Sequence Information (all 12)
    ORTHOLOGY for pon2 (Chr: 16)
    CITATIONS (21)