Gene

vps51

ID
ZDB-GENE-030131-6008
Name
VPS51 subunit of GARP complex
Symbol
vps51 Nomenclature History
Previous Names
  • ang2 (1)
  • c11orf2
  • fat free (1)
  • fat-free (1)
  • ffr (1)
  • fi30b05
  • wu:fi30b05
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Enables small GTPase binding activity. Involved in endocytic recycling; lysosomal transport; and retrograde transport, endosome to Golgi. Acts upstream of or within several processes, including Golgi organization; lipid digestion; and regulation of phospholipase activity. Predicted to be located in recycling endosome. Predicted to be part of EARP complex and GARP complex. Is expressed in digestive system; head; heart; and trunk musculature. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia. Orthologous to human VPS51 (VPS51 subunit of GARP complex).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
9 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With vps51 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
pontocerebellar hypoplasia type 13 Alliance Pontocerebellar hypoplasia, type 13 618606
Associated With vps51 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR014812 Vacuolar protein sorting-associated protein 51
Homologous_superfamily IPR016159 Cullin repeat-like-containing domain superfamily
Domain Details Per Protein
Protein Length Cullin repeat-like-containing domain superfamily Vacuolar protein sorting-associated protein 51
UniProtKB:F1QLF1 827
UniProtKB:Q155U0 827
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations