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ZIRC
ZFIN ID: ZDB-GENE-030131-5455
Gene Name: DnaJ heat shock protein family (Hsp40) member B1b
Gene Symbol: dnajb1b    Nomenclature History

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Previous Names: fd19c10, wu:fd19c10, zgc:55492

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have chaperone binding activity and unfolded protein binding activity. Involved in lens development in camera-type eye. Predicted to localize to the cytosol. Is expressed in lens; neural plate; optic tectum; and solid lens vesicle. Orthologous to human DNAJB1 (DnaJ heat shock protein family (Hsp40) member B1).
Genome Resources: Alliance (1),  Gene:327244 (1),  Ensembl(GRCz11):ENSDARG00000041394 (2)
GENE EXPRESSION
All Expression Data: 6 figures from 2 publications
Directly Submitted Expression Data: 5 figures (5 images) from Thisse et al., 2004 [MGC:55492]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa32788 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko1137a Small Deletion Unknown Unknown CRISPR
    zko1137b Small Deletion Unknown Unknown CRISPR
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-dnajb1b 1
    MO1-dnajb1b N/A 1
    MO2-dnajb1b N/A 1
    PHENOTYPE
    Data: 2 figures from Khan et al., 2016
    Observed in:
    DISEASE ASSOCIATED WITH dnajb1b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dnajb1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process lens development in camera-type eye (more)
    Cellular Component cytosol (more)
    Molecular Function unfolded protein binding (more)
    GO Terms (all 6)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dnajb1b-201 (1)    Ensembl 1942
    ncRNA dnajb1b-002 (1) 745
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dnajb1b No data available
    MARKER RELATIONSHIPS
    dnajb1b Contained in: [BAC] CH73-341P18 (1) (order this)
    dnajb1b Encodes: [EST] fd19c10
    [cDNA] MGC:55492 (1) (order this), MGC:191316 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_199773 (1) 1751 bp
    Genomic GenBank:CU571167 (1) 122272 bp
    Select Tool
    Polypeptide UniProtKB:B8JM56 (1) 340 aa
    Sequence Clusters UniGene:26675 (1)
    Sequence Information (all 16)
    ORTHOLOGY for dnajb1b ( Chr: 1 )
    CITATIONS (24)