ZFIN ID: ZDB-GENE-030131-4683
Gene Name: tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)
Gene Symbol: tsku    Nomenclature History

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Previous Names: tsk, fd51d02, tsukushi (1), wu:fd51d02, zgc:56201

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to be involved in multicellular organism development. Predicted to localize to the extracellular matrix and extracellular space. Is expressed in several structures, including germ ring; mesoderm; pectoral fin bud; tail bud; and yolk syncytial layer. Orthologous to human TSKU (tsukushi, small leucine rich proteoglycan).
Genome Resources: Alliance (1),  Gene:325958 (1),  Ensembl(GRCz11):ENSDARG00000040815 (2)
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 6 figures (20 images) from Thisse et al., 2008 [cssl:d0345]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la012716Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la027632Tg Transgenic Insertion Unknown Unknown DNA
    sa35911 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tsku HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH tsku VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process multicellular organism development (more)
    Cellular Component extracellular region (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Homologous_superfamily IPR032675 Leucine-rich repeat domain superfamily
    Repeat IPR001611 Leucine-rich repeat
    Repeat IPR003591 Leucine-rich repeat, typical subtype
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tsku-201 (1)    Ensembl 2403
    tsku-202 (1)    Ensembl 2262
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tsku No data available
    MARKER RELATIONSHIPS
    tsku Contained in: [BAC] DKEY-52L18 (1) (order this)
    tsku Encodes: [EST] cssl:d0345 (1), fd51d02, IMAGE:7142286 (1)
    [cDNA] MGC:56201 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_199733 (1) 2418 nt
    Genomic GenBank:BX537138 (1) 144274 nt
    Select Tool
    Polypeptide UniProtKB:A8BB59 (1) 366 aa
    Sequence Information (all 24)
    ORTHOLOGY for tsku ( Chr: 15 )
    CITATIONS (31)