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Gene

setb

ID
ZDB-GENE-030131-433
Name
SET nuclear proto-oncogene b
Symbol
setb Nomenclature History
Previous Names
  • wu:fb30g11
  • wu:fd16c08
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to enable chromatin binding activity and histone binding activity. Acts upstream of or within neuromast development. Predicted to be active in chromatin and nucleus. Is expressed in several structures, including digestive system; nervous system; optic cup; otic vesicle; and tail bud. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability. Orthologous to human SET (SET nuclear proto-oncogene).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Serifi et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With setb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Mental retardation, autosomal dominant 58 618106
Associated With setb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR002164 Nucleosome assembly protein (NAP)
Homologous_superfamily IPR037231 NAP-like superfamily
Domain Details Per Protein
Protein Length NAP-like superfamily Nucleosome assembly protein (NAP)
UniProtKB:F1R3I6 275
UniProtKB:Q6TGU0 275
UniProtKB:A0A2R8QJ70 287
UniProtKB:Q6NYZ1 268
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-set polyclonal Rabbit
  • IHC
1
Ab2-set polyclonal Goat
  • WB
Santa Cruz Biotechnology, Inc.
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations