Gene

sdcbp2

ID
ZDB-GENE-030131-3727
Name
syndecan binding protein (syntenin) 2
Symbol
sdcbp2 Nomenclature History
Previous Names
  • sdcbp
  • syntenin-a (1)
  • wu:fc51c03
  • wu:fk31e01
  • zgc:55679
  • zgc:77716
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Exhibits phosphatidylinositol-3,4-bisphosphate binding activity and syndecan binding activity. Involved in several processes, including epiboly involved in gastrulation with mouth forming second; response to hypoxia; and synapse assembly. Predicted to localize to cytoplasm and plasma membrane. Is expressed in gill; oocyte; and spinal cord. Orthologous to several human genes including SDCBP2 (syndecan binding protein 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sdcbp2 Human Ortholog
No data available
Associated With sdcbp2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001478 PDZ domain
Domain IPR041489 PDZ domain 6
Homologous_superfamily IPR036034 PDZ superfamily
Domain Details Per Protein
Protein Length PDZ domain PDZ domain 6 PDZ superfamily
UniProtKB:Q803J6 299
UniProtKB:E9QBZ6 267
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-sdcbp Rabbit
  • IHC
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Note
Woods, et al. (2005. Genome Res. 15:1307-1314.) report this gene to be sdcbp based on amino acid similarity to human SDCBP. Subsequent analysis suggests it is the ortholog of human SDCBP2 and mouse Sdcbp2 based on amino acid similarity and conserved synteny.
Citations