Gene
sdcbp2
- ID
- ZDB-GENE-030131-3727
- Name
- syndecan binding protein (syntenin) 2
- Symbol
- sdcbp2 Nomenclature History
- Previous Names
-
- sdcbp
- syntenin-a (1)
- wu:fc51c03
- wu:fk31e01
- zgc:55679
- zgc:77716
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Exhibits phosphatidylinositol-3,4-bisphosphate binding activity and syndecan binding activity. Involved in several processes, including epiboly involved in gastrulation with mouth forming second; response to hypoxia; and synapse assembly. Predicted to localize to cytoplasm and plasma membrane. Is expressed in gill and spinal cord. Orthologous to several human genes including SDCBP2 (syndecan binding protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55679 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Amyloid-beta A4 Precursor Protein-Binding | PDZ domain | PDZ superfamily |
|---|---|---|---|---|
|
UniProtKB:Q803J6
|
299 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
sdcbp2-201
(1)
|
Ensembl | 2,508 nt | ||
| mRNA |
sdcbp2-202
(1)
|
Ensembl | 864 nt | ||
| mRNA |
sdcbp2-203
(1)
|
Ensembl | 934 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance
- Gene Tree
- Ensembl
- Note
- Woods, et al. (2005. Genome Res. 15:1307-1314.) report this gene to be sdcbp based on amino acid similarity to human SDCBP. Subsequent analysis suggests it is the ortholog of human SDCBP2 and mouse Sdcbp2 based on amino acid similarity and conserved synteny.