ZFIN ID: ZDB-GENE-030131-3633
Gene Name: semaphorin 7A
Gene Symbol: sema7a    Nomenclature History

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Previous Names: fc47g07, wu:fc47g07 (1), zgc:174881 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to have chemorepellent activity; integrin binding activity; and semaphorin receptor binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; generation of neurons; and positive regulation of macromolecule metabolic process. Predicted to localize to integral component of plasma membrane. Is expressed in Purkinje cell. Orthologous to human SEMA7A (semaphorin 7A (John Milton Hagen blood group)).
Genome Resources: Alliance (1),  Gene:324910 (1),  Ensembl(GRCz11):ENSDARG00000078707 (2)
GENE EXPRESSION
All Expression Data: Fig. 7 from Takeuchi et al., 2017
Wild-type Stages, Structures: Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
High Throughput Expression: Expression Atlas (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH sema7a HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
[Blood group, John-Milton-Hagen system] 614745
DISEASE ASSOCIATED WITH sema7a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process axon guidance (more)
Cellular Component integral component of plasma membrane (more)
Molecular Function semaphorin receptor binding (more)
GO Terms (all 15)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA sema7a-201 (1)    Ensembl 3134
sema7a-202 (1)    Ensembl 1365
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM sema7a No data available
MARKER RELATIONSHIPS
sema7a Contained in: [BAC] DKEY-42P14 (1) (order this), DKEYP-73B11 (1)
sema7a Encodes: [EST] fc47g07
[cDNA] MGC:174881 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001114885 (1) 1440 nt
Genomic GenBank:CR391977 (1) 189510 nt
Select Tool
Polypeptide UniProtKB:E7FBE1 (1) 640 aa
Sequence Information (all 16)
ORTHOLOGY for sema7a ( Chr: 25 )
CITATIONS (18)