Gene

sema7a

ID
ZDB-GENE-030131-3633
Name
semaphorin 7A
Symbol
sema7a Nomenclature History
Previous Names
  • fc47g07
  • wu:fc47g07 (1)
  • zgc:174881 (1)
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have chemorepellent activity; integrin binding activity; and semaphorin receptor binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; generation of neurons; and positive regulation of macrophage cytokine production. Predicted to localize to integral component of plasma membrane. Is expressed in Purkinje cell. Orthologous to human SEMA7A (semaphorin 7A (John Milton Hagen blood group)).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Takeuchi et al., 2017
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sema7a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
[Blood group, John-Milton-Hagen system] 614745
Associated With sema7a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001627 Sema domain
Domain IPR007110 Immunoglobulin-like domain
Domain IPR016201 PSI domain
Family IPR027231 Semaphorin
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Homologous_superfamily IPR036352 Sema domain superfamily
Domain Details Per Protein
Protein Length Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold PSI domain Sema domain Sema domain superfamily Semaphorin WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:A9JTC9 431
UniProtKB:X1WHP4 431
UniProtKB:E7FBE1 640
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations