ZFIN ID: ZDB-GENE-030131-321
Gene Name: cyclin-dependent kinase 9 (CDC2-related kinase)
Gene Symbol: cdk9    Nomenclature History

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Previous Names: wu:fb22e09, wu:fc06c02

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have several functions, including cyclin binding activity; protein serine/threonine kinase activity; and transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including cardiac muscle tissue regeneration; inflammatory response to wounding; and regulation of cardiac muscle cell proliferation. Predicted to localize to cyclin/CDK positive transcription elongation factor complex and nuclear chromatin. Orthologous to human CDK9 (cyclin dependent kinase 9).
Genome Resources: Alliance (1),  Gene:321602 (1),  Ensembl(GRCz11):ENSDARG00000044811 (1)
GENE EXPRESSION
All Expression Data: 5 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:66392]
  1 figure (1 image) from Thisse et al., 2005 [eu149]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:7163467]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ed9 Small Deletion Exon 2 Frameshift, Premature Stop CRISPR
sa14013 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • z38 Small Deletion Unknown Unknown TALEN
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-cdk9 1
    MO1-cdk9 N/A 1
    MO2-cdk9 N/A 1
    MO3-cdk9 N/A 5
    MO4-cdk9 N/A 1
    MO5-cdk9 N/A 1
    MO6-cdk9 N/A 1
    MO7-cdk9 N/A 1
    MO8-cdk9 N/A 1
    MO9-cdk9 N/A 1
    MO10-cdk9 N/A 1
    MO11-cdk9 N/A 1
    MO12-cdk9 N/A 1
    MO13-cdk9 N/A 2
    MO14-cdk9 N/A 1
    MO15-cdk9 N/A 1
    TALEN1-cdk9 1
    DISEASE ASSOCIATED WITH cdk9 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cdk9 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein-containing complex assembly (more)
    Cellular Component cytoplasm (more)
    Molecular Function ATP binding (more)
    GO Terms (all 20)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cdk9-201 (1)    Ensembl 1782
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cdk9 No data available
    MARKER RELATIONSHIPS
    cdk9 Contained in: [BAC] DKEY-93M18 (1) (order this)
    cdk9 Contains: [SNP] rs3729067 (1)
    cdk9 Encodes: [EST] eu149 (1), fb22e09, fc06c02, IMAGE:7163467 (1)
    [cDNA] MGC:66392 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_212591 (1) 1768 nt
    Genomic GenBank:BX530036 (1) 211643 nt Blast at MegaBLAST
    Polypeptide UniProtKB:Q7SXE8 (1) 374 aa
    Sequence Information (all 17)
    ORTHOLOGY for cdk9 ( Chr: 21 )
    CITATIONS (36)