Gene

cyp26b1

ID
ZDB-GENE-030131-2908
Name
cytochrome P450, family 26, subfamily b, polypeptide 1
Symbol
cyp26b1 Nomenclature History
Previous Names
  • dol
  • fc21d03
  • stocksteif (1)
  • wu:fc21d03
  • wu:fc26h10
  • zgc:76999
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have retinoic acid 4-hydroxylase activity. Involved in several processes, including animal organ morphogenesis; negative regulation of retinoic acid receptor signaling pathway; and retinoic acid catabolic process. Predicted to localize to endoplasmic reticulum and endoplasmic reticulum membrane. Is expressed in several structures, including brain; cranium; hindbrain neural keel; pectoral fin; and pleuroperitoneal region. Orthologous to human CYP26B1 (cytochrome P450 family 26 subfamily B member 1).
Genome Resources
Note
None
Expression
All Expression Data
40 figures from 26 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
24 figures from 9 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cyp26b1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Craniosynostosis with radiohumeral fusions and other skeletal and craniofacial anomalies 614416
Associated With cyp26b1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017972 Cytochrome P450, conserved site
Family IPR001128 Cytochrome P450
Family IPR002403 Cytochrome P450, E-class, group IV
Homologous_superfamily IPR036396 Cytochrome P450 superfamily
Domain Details Per Protein
Protein Length Cytochrome P450 Cytochrome P450, conserved site Cytochrome P450, E-class, group IV Cytochrome P450 superfamily
UniProtKB:A0A0R4I9F4 511
UniProtKB:Q6EIG3 511
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations