ZFIN ID: ZDB-GENE-030131-2908
Gene Name: cytochrome P450, family 26, subfamily b, polypeptide 1
Gene Symbol: cyp26b1
Previous Names: dol, fc21d03, stocksteif (1), wu:fc21d03, wu:fc26h10, zgc:76999
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 36 figures from 21 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  brain, ceratobranchial cartilage perichondrium, ceratohyal cartilage perichondrium, cerebellum (all 65) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
la025910Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa2 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa3 Point Mutation ENU
    t24295 Unknown
  • European Zebrafish Resource Center (EZRC) (order this)
  • ti230g Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-cyp26b1 (1), MO2-cyp26b1 (1), MO3-cyp26b1 (1), MO4-cyp26b1 (1), MO5-cyp26b1 (1)
    PHENOTYPE
    Data: 20 figures from 8 publications
    Observed in: basibranchial, basihyal cartilage, bone element, cartilage development (all 56) expand
    DISEASE ASSOCIATED WITH cyp26b1 HUMAN ORTHOLOG 
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Craniosynostosis with radiohumeral fusions and other skeletal and craniofacial anomalies 614416
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process negative regulation of retinoic acid receptor signaling pathway (more)
    Cellular Component endoplasmic reticulum (more)
    Molecular Function 1-hydroxypyrene 6,7-monooxygenase activity (more)
    GO Terms (all 59)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001128 (1)
  • InterPro:IPR002403 (1)
  • InterPro:IPR017972 (1)
  • PROSITE:PS00086 (1)
  • Pfam:PF00067 (1)
  • EC:1.14.-.- (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cyp26b1-001 (1) 3869
    ncRNA cyp26b1-002 (1) 579
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cyp26b1
    TgBAC(cyp26b1:Citrine)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    cyp26b1Contained in: [BAC] CH73-51F7 (1) (order this), CH73-368P22 (1) (order this), CH211-197C14 (order this)
    cyp26b1Encodes: [EST] fc21d03, fc26h10 (1)
    [cDNA] MGC:76999 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212666 (1) 3348bp
    Genomic GenBank:AL935122 198363bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4I9F4 (1) 511aa
    Sequence Clusters UniGene:76359 (1)
    Sequence Information (all 18)
    OTHER cyp26b1 GENE PAGES 
  • Gene:324188 (1)
  • VEGA:OTTDARG00000035532 (1)
  • Ensembl(GRCz10):ENSDARG00000077121 (1)
  • ORTHOLOGY for cyp26b1 (Chr: 7) 
    Species Symbol Chromosome Accession # Evidence
    Human CYP26B1 2
  • Gene:56603
  • OMIM:605207
  • HGNC:20581
  • Amino acid sequence comparison (3)
    Conserved genome location (synteny) (1)
    Mouse Cyp26b1 6
  • MGI:2176159
  • Gene:232174
  • Amino acid sequence comparison (3)
    Conserved genome location (synteny) (2)
    Download Curated Orthology
    CITATIONS (67)