ZFIN ID: ZDB-GENE-030131-2860
Gene Name: serum/glucocorticoid regulated kinase 1
Gene Symbol: sgk1    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: sgk (1), cb1083 (1), wu:fc20a09

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have potassium channel regulator activity and protein serine/threonine kinase activity. Involved in inflammatory response. Predicted to localize to cytoplasm and nucleus. Is expressed in several structures, including blood vasculature; epidermal cell; epiphysis; pronephric duct; and ventral mesoderm. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human SGK1 (serum/glucocorticoid regulated kinase 1).
Genome Resources: Alliance (1),  Gene:324140 (1),  Ensembl(GRCz11):ENSDARG00000025522 (1)
GENE EXPRESSION
All Expression Data: 16 figures from 7 publications
Directly Submitted Expression Data: 5 figures (17 images) from Thisse et al., 2001 [cb1083]
  6 figures (12 images) from Thisse et al., 2004 [IMAGE:6912555]
Wild-type Stages, Structures: Blastula:Dome (4.33h-4.66h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la022654Tg Transgenic Insertion Unknown Unknown DNA
sa3228 Point Mutation Unknown Premature Stop ENU
sa24374 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-sgk1 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH sgk1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH sgk1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process inflammatory response (more)
    Cellular Component cytoplasm (more)
    Molecular Function ATP binding (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA sgk1-201 (1)    Ensembl 2320
    sgk1-202 (1)    Ensembl 845
    sgk1-203 (1)    Ensembl 799
    sgk1-204 (1)    Ensembl 1143
    ncRNA sgk1-004 (1)    Ensembl 649
    sgk1-006 (1)    Ensembl 844
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM sgk1 No data available
    MARKER RELATIONSHIPS
    sgk1 Contained in: [BAC] DKEY-161P7 (1) (order this)
    sgk1 Encodes: [EST] cb1083 (1) (order this), fc20a09, IMAGE:6912555 (1)
    [cDNA] MGC:56646 (1), MGC:85778 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_199212 (1) 2339 nt
    Genomic GenBank:BX927365 (1) 229608 nt Blast at MegaBLAST
    Polypeptide UniProtKB:Q7ZTW4 (1) 433 aa
    Sequence Information (all 28)
    ORTHOLOGY for sgk1 ( Chr: 23 )
    CITATIONS (43)