ZFIN ID: ZDB-GENE-030131-1074
Gene Name: apolipoprotein C-I
Gene Symbol: apoc1    Nomenclature History

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Previous Names: apoc1l, fb58g10, wu:fb58g10

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have fatty acid binding activity and phospholipase inhibitor activity. Involved in cell migration involved in gastrulation. Predicted to localize to high-density lipoprotein particle and very-low-density lipoprotein particle. Is expressed in DEL; blastoderm; and liver. Human ortholog(s) of this gene implicated in Alzheimer's disease and obesity. Orthologous to human APOC1 (apolipoprotein C1).
Genome Resources: Alliance (1),  Gene:570638 (1),  Ensembl(GRCz11):ENSDARG00000092170 (2)
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-apoc1
3
MO1-apoc1 N/A 1
MO2-apoc1 N/A 1
MO3-apoc1 N/A 1
DISEASE ASSOCIATED WITH apoc1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH apoc1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cell migration involved in gastrulation (more)
Cellular Component extracellular region (more)
Molecular Function fatty acid binding (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA apoc1-201 (1)    Ensembl 777
apoc1-202 (1)    Ensembl 783
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab1-apoc1 polyclonal Rabbit 1
Ab2-apoc1 polyclonal Rabbit 1
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM apoc1 No data available
MARKER RELATIONSHIPS
apoc1 Contained in: [BAC] DKEY-7F3 (1) (order this)
apoc1 Contains: [SNP] rs3728783 (1), rs3728784 (1)
apoc1 Encodes: [EST] fb58g10, IMAGE:7015412
apoc1 Has Artifact: [cDNA] MGC:173647 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001291886 (1)
Genomic GenBank:BX004983 (1) 234489 nt Blast at MegaBLAST
Polypeptide UniProtKB:E9QDI1 (1) 85 aa
Sequence Information (all 18)
ORTHOLOGY for apoc1 ( Chr: 16 )
CITATIONS (30)