ZFIN ID: ZDB-GENE-030130-1
Gene Name: erythrocyte membrane protein band 4.1b
Gene Symbol: epb41b    Nomenclature History

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Previous Names: epb41, P4.1R (1), cha (1), chablis (1), merlot, mot, protein 4.1R (1), wu:fb70c02 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Exhibits calmodulin binding activity. Involved in embryonic hemopoiesis and erythrocyte differentiation. Localizes to extrinsic component of plasma membrane. Is expressed in blood; liver; ovary; and pericardial region. Human ortholog(s) of this gene implicated in hereditary elliptocytosis. Orthologous to human EPB41 (erythrocyte membrane protein band 4.1).
Genome Resources: Alliance (1),  Gene:326287 (1),  Ensembl(GRCz11):ENSDARG00000029019 (2)
GENE EXPRESSION
All Expression Data: 8 figures from 3 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
DISEASE ASSOCIATED WITH epb41b HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hereditary elliptocytosis Alliance Elliptocytosis-1 611804
DISEASE ASSOCIATED WITH epb41b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process embryonic hemopoiesis (more)
Cellular Component extrinsic component of plasma membrane (more)
Molecular Function calmodulin binding (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA epb41b-201 (1)    Ensembl 5160
ncRNA epb41b-002 (1)    Ensembl 500
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab1-epb41 polyclonal Rabbit IHC, WB 2
Ab2-epb41 polyclonal Rabbit IHC, WB 2
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM epb41b No data available
MARKER RELATIONSHIPS
epb41b Contained in: [BAC] CH211-168I6 (1), DKEY-108F8 (1) (order this)
epb41b Encodes: [EST] fb70c02 (1)
[cDNA] MGC:193936 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_175084 (1) 5097 nt
Genomic GenBank:CR391910 (1) 186084 nt
Select Tool
Polypeptide UniProtKB:Q8JG61 (1) 1534 aa
Sequence Information (all 14)
ORTHOLOGY for epb41b ( Chr: 16 )
CITATIONS (38)