Gene

msna

ID
ZDB-GENE-021211-2
Name
moesin a
Symbol
msna Nomenclature History
Previous Names
  • msn1 (1)
  • moesin1 (1)
  • moesin (1)
  • rdx
  • wu:fb14b03
  • zgc:85640
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have actin binding activity. Involved in blood vessel lumenization and endoderm development. Predicted to localize to cytoplasm; cytoskeleton; and plasma membrane. Is expressed in several structures, including cardiovascular system; gut; hypochord; nervous system; and swim bladder bud. Human ortholog(s) of this gene implicated in immunodeficiency 50. Orthologous to human MSN (moesin).
Genome Resources
Note
None
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With msna Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
immunodeficiency 50 Alliance Immunodeficiency 50 300988
Associated With msna Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019747 FERM conserved site
Domain IPR000299 FERM domain
Domain IPR011259 Ezrin/radixin/moesin, C-terminal
Domain IPR018979 FERM, N-terminal
Domain IPR018980 FERM, C-terminal PH-like domain
Domain IPR019748 FERM central domain
Domain IPR019749 Band 4.1 domain
Domain IPR041789 ERM family, FERM domain C-lobe
Family IPR000798 Ezrin/radixin/moesin-like
Family IPR011174 Ezrin/radixin/moesin
Homologous_superfamily IPR008954 Moesin tail domain superfamily
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR014352 FERM/acyl-CoA-binding protein superfamily
Homologous_superfamily IPR029071 Ubiquitin-like domain superfamily
Homologous_superfamily IPR035963 FERM superfamily, second domain
Domain Details Per Protein
Protein Length Band 4.1 domain ERM family, FERM domain C-lobe Ezrin/radixin/moesin Ezrin/radixin/moesin, C-terminal Ezrin/radixin/moesin-like FERM/acyl-CoA-binding protein superfamily FERM central domain FERM conserved site FERM, C-terminal PH-like domain FERM domain FERM, N-terminal FERM superfamily, second domain Moesin tail domain superfamily PH-like domain superfamily Ubiquitin-like domain superfamily
UniProtKB:Q7ZWC7 439
UniProtKB:A0A2R8Q5G6 570
UniProtKB:Q66I42 579
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations