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ZIRC
ZFIN ID: ZDB-GENE-021211-2
Gene Name: moesin a
Gene Symbol: msna    Nomenclature History

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Previous Names: msn1 (1), moesin1 (1), moesin (1), rdx, wu:fb14b03, zgc:85640

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have actin binding activity. Involved in blood vessel lumenization and endoderm development. Predicted to localize to the cytoskeleton. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is expressed in several structures, including cardiovascular system; gut; hypochord; nervous system; and swim bladder bud. Orthologous to human MSN (moesin).
Genome Resources: Alliance (1),  Gene:286739 (1),  Ensembl(GRCz11):ENSDARG00000058128 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la024860Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa267 Point Mutation Unknown Premature Stop ENU
    sa1265 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18450 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20388 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33578 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-msna N/A 1
    MO2-msna N/A 1
    MO3-msna N/A 1
    MO4-msna N/A 1
    TALEN1-msna
    1
    DISEASE ASSOCIATED WITH msna HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Immunodeficiency 50 300988
    DISEASE ASSOCIATED WITH msna VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process endoderm development (more)
    Cellular Component cytoskeleton (more)
    Molecular Function actin binding (more)
    GO Terms (all 5)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA msna-201 (1)    Ensembl 3780
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM msna
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(kdrl:msna-EGFP) kdrl EGFPmsna Danio rerio 1 9
    MARKER RELATIONSHIPS
    msna Contained in: [BAC] CH73-95F18 (1) (order this), DKEY-286F3 (1) (order this)
    msna Encodes: [EST] eu2457 (1), fb14b03 (1)
    [cDNA] MGC:85640 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001004296 (1) 3635 bp
    Genomic GenBank:CR812469 (1) 162086 bp
    Select Tool
    Polypeptide UniProtKB:Q66I42 (1) 579 aa
    Sequence Clusters UniGene:76301 (1)
    Sequence Information (all 23)
    ORTHOLOGY for msna ( Chr: 5 )
    CITATIONS (45)