Gene

grm6b

ID
ZDB-GENE-021120-2
Name
glutamate receptor, metabotropic 6b
Symbol
grm6b Nomenclature History
Previous Names
  • grma
  • cb496 (1)
  • mglur6b (1)
  • zgc:158329
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have group III metabotropic glutamate receptor activity. Involved in detection of light stimulus involved in visual perception. Predicted to localize to integral component of plasma membrane. Is expressed in forebrain; pharynx; and retina. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1B. Orthologous to human GRM6 (glutamate metabotropic receptor 6).
Genome Resources
Note
None
Expression
All Expression Data
7 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Huang et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With grm6b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital stationary night blindness 1B Alliance Night blindness, congenital stationary (complete), 1B, autosomal recessive 257270
Associated With grm6b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017979 GPCR, family 3, conserved site
Domain IPR001828 Receptor, ligand binding region
Domain IPR011500 GPCR, family 3, nine cysteines domain
Domain IPR017978 GPCR family 3, C-terminal
Family IPR000162 GPCR, family 3, metabotropic glutamate receptor
Family IPR000337 GPCR, family 3
Family IPR001786 GPCR, family 3, metabotropic glutamate receptor 4
Homologous_superfamily IPR028082 Periplasmic binding protein-like I
Homologous_superfamily IPR038550 GPCR, family 3, nine cysteines domain superfamily
Domain Details Per Protein
Protein Length GPCR, family 3 GPCR, family 3, conserved site GPCR family 3, C-terminal GPCR, family 3, metabotropic glutamate receptor GPCR, family 3, metabotropic glutamate receptor 4 GPCR, family 3, nine cysteines domain GPCR, family 3, nine cysteines domain superfamily Periplasmic binding protein-like I Receptor, ligand binding region
UniProtKB:F1Q5Q6 893
UniProtKB:F6P3F9 909
UniProtKB:Q7SZW9 419
UniProtKB:A1L1T5 905
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-grm6b polyclonal Rabbit
  • IHC
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations