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Gene

rdh8a

ID
ZDB-GENE-021115-3
Name
retinol dehydrogenase 8a
Symbol
rdh8a Nomenclature History
Previous Names
  • rdh8
  • cb501 (1)
  • zf 1.1 (1)
  • zfprRDH2 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to enable NADP-retinol dehydrogenase activity and estradiol 17-beta-dehydrogenase activity. Predicted to act upstream of or within estrogen biosynthetic process. Predicted to be located in cytoplasm and membrane. Is expressed in several structures, including anterior axial hypoblast; epidermis; nervous system; polster; and tail bud. Orthologous to human RDH8 (retinol dehydrogenase 8).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rdh8a Human Ortholog
No data available
Associated With rdh8a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020904 Short-chain dehydrogenase/reductase, conserved site
Family IPR002347 Short-chain dehydrogenase/reductase SDR
Family IPR011348 17beta-dehydrogenase
Homologous_superfamily IPR036291 NAD(P)-binding domain superfamily
Domain Details Per Protein
Protein Length 17beta-dehydrogenase NAD(P)-binding domain superfamily Short-chain dehydrogenase/reductase, conserved site Short-chain dehydrogenase/reductase SDR
UniProtKB:Q6PC70 318
UniProtKB:Q7T2I8 318
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations