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ZIRC
ZFIN ID: ZDB-GENE-021015-3
Gene Name: STT3 oligosaccharyltransferase complex catalytic subunit A
Gene Symbol: stt3a    Nomenclature History

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Previous Names: cb437 (1), itm1, wu:fb38c11

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have oligosaccharyl transferase activity. Predicted to be involved in protein glycosylation. Predicted to localize to the integral component of membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Iw. Is expressed in axial mesoderm; hatching gland; musculature system; notochord; and otic placode. Orthologous to human STT3A (STT3 oligosaccharyltransferase complex catalytic subunit A).
Genome Resources: Alliance (1),  Gene:266797 (1),  Ensembl(GRCz11):ENSDARG00000104953 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (12 images) from Thisse et al., 2001 [cb437]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:7143563]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la017566Tg Transgenic Insertion Unknown Unknown DNA
sa17071 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21794 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH stt3a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    congenital disorder of glycosylation Iw Alliance ?Congenital disorder of glycosylation, type Iw 615596
    DISEASE ASSOCIATED WITH stt3a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein glycosylation (more)
    Cellular Component integral component of membrane (more)
    Molecular Function oligosaccharyl transferase activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003674 (1)
  • Pfam:PF02516 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA stt3a-201 (1)    Ensembl 2071
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM stt3a No data available
    MARKER RELATIONSHIPS
    stt3a Contained in: [Fosmid] CH1073-74N1 (1) (order this)
    stt3a Encodes: [EST] cb437 (1) (order this), fb38c11 (1), IMAGE:7143563 (1) (order this)
    [cDNA] MGC:56322 (1) (order this), MGC:77796 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_201458 (1) 2608 bp
    Genomic GenBank:CU633886 (1) 32822 bp
    Select Tool
    Polypeptide UniProtKB:Q7ZUY9 (1) 705 aa
    Sequence Clusters UniGene:75539 (1)
    Sequence Information (all 21)
    ORTHOLOGY for stt3a ( Chr: 10 )
    CITATIONS (27)