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ZIRC
ZFIN ID: ZDB-GENE-020919-2
Gene Name: SEC31 homolog A, COPII coat complex component
Gene Symbol: sec31a    Nomenclature History

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Previous Names: sec31p, cb354 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have structural molecule activity. Involved in digestive system development; endoplasmic reticulum organization; and liver development. Predicted to localize to the COPII vesicle coat and endoplasmic reticulum exit site. Is expressed in several structures, including alar plate midbrain region; axis; digestive system; fin; and midbrain. Orthologous to human SEC31A (SEC31 homolog A, COPII coat complex component).
Genome Resources: Alliance (1),  Gene:266638 (1),  Ensembl(GRCz11):ENSDARG00000021082 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la011909Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la027204Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la027205Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa1082 Point Mutation Unknown Premature Stop ENU
    sa31763 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34821 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41581 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-sec31a N/A 2
    DISEASE ASSOCIATED WITH sec31a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    ?Neurodevelopmental disorder with spastic quadriplegia, optic atrophy, seizures, and structural brain anomalies 618651
    DISEASE ASSOCIATED WITH sec31a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process digestive system development (more)
    Cellular Component COPII vesicle coat (more)
    Molecular Function structural molecule activity (more)
    GO Terms (all 17)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA sec31a-202 (1)    Ensembl 4414
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-sec31a Rabbit IHC, WB 1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM sec31a No data available
    MARKER RELATIONSHIPS
    sec31a Contained in: [BAC] CH211-249H16 (1) (order this)
    sec31a Encodes: [EST] cb354 (1) (order this), wz12226 (1)
    [cDNA] MGC:63547 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_199530 (1) 4443 bp
    Genomic GenBank:CR847788 (1) 176964 bp
    Select Tool
    Polypeptide UniProtKB:Q7SYD5 (1) 1254 aa
    Sequence Clusters UniGene:19511 (1)
    Sequence Information (all 31)
    ORTHOLOGY for sec31a ( Chr: 10 )
    CITATIONS (27)