Gene

mst1

ID
ZDB-GENE-020806-3
Name
macrophage stimulating 1
Symbol
mst1 Nomenclature History
Previous Names
  • msp (1)
  • cb981 (1)
  • hgfl1 (1)
  • macrophage-stimulating protein (1)
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have serine-type endopeptidase activity. Involved in bone mineralization and inflammatory response. Is expressed in digestive system; margin; and yolk syncytial layer. Used to study inflammatory bowel disease. Orthologous to several human genes including MST1 (macrophage stimulating 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mst1 Human Ortholog
No data available
Associated With mst1 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018056 Kringle, conserved site
Domain IPR000001 Kringle
Domain IPR001254 Serine proteases, trypsin domain
Domain IPR003609 PAN/Apple domain
Family IPR001314 Peptidase S1A, chymotrypsin family
Family IPR024174 Hepatocyte growth factor/Macrophage stimulatory protein
Homologous_superfamily IPR009003 Peptidase S1, PA clan
Homologous_superfamily IPR013806 Kringle-like fold
Homologous_superfamily IPR038178 Kringle superfamily
Homologous_superfamily IPR043504 Peptidase S1, PA clan, chymotrypsin-like fold
Domain Details Per Protein
Protein Length Hepatocyte growth factor/Macrophage stimulatory protein Kringle Kringle, conserved site Kringle-like fold Kringle superfamily PAN/Apple domain Peptidase S1A, chymotrypsin family Peptidase S1, PA clan Peptidase S1, PA clan, chymotrypsin-like fold Serine proteases, trypsin domain
UniProtKB:Q90ZN6 709
UniProtKB:Q5XFY1 709
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations