Gene

mpp5a

ID
ZDB-GENE-020712-1
Name
membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5)
Symbol
mpp5a Nomenclature History
Previous Names
  • mpp5
  • nagie oko
  • nok
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to have ATP binding activity. Involved in several processes, including animal organ development; apical protein localization; and morphogenesis of an epithelium. Localizes to several cellular components, including apical junction complex; intrinsic component of plasma membrane; and photoreceptor inner segment. Is expressed in several structures, including EVL; brain; eye; neural tube; and photoreceptor cell. Orthologous to human MPP5 (membrane palmitoylated protein 5).
Genome Resources
Note
None
Expression
All Expression Data
16 figures from 9 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
41 figures from 23 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mpp5a Human Ortholog
No data available
Associated With mpp5a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020590 Guanylate kinase, conserved site
Domain IPR001452 SH3 domain
Domain IPR001478 PDZ domain
Domain IPR004172 L27 domain
Domain IPR008144 Guanylate kinase-like domain
Domain IPR008145 Guanylate kinase/L-type calcium channel beta subunit
Domain IPR014775 L27 domain, C-terminal
Domain IPR015145 L27-N
Domain IPR035601 MPP5, SH3 domain
Family IPR031185 MAGUK p55 subfamily member 5-like
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036028 SH3-like domain superfamily
Homologous_superfamily IPR036034 PDZ superfamily
Homologous_superfamily IPR036892 L27 domain superfamily
Domain Details Per Protein
Protein Length Guanylate kinase, conserved site Guanylate kinase-like domain Guanylate kinase/L-type calcium channel beta subunit L27 domain L27 domain, C-terminal L27 domain superfamily L27-N MAGUK p55 subfamily member 5-like MPP5, SH3 domain PDZ domain PDZ superfamily P-loop containing nucleoside triphosphate hydrolase SH3 domain SH3-like domain superfamily
UniProtKB:Q1LVF4 703
UniProtKB:B3DIW9 703
UniProtKB:Q8JHF4 677
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-mpp5a Rabbit
  • IHC
1
Ab3-mpp5a polyclonal Rabbit
  • IHC
  • WB
9
Ab2-mpp5a polyclonal Rabbit
  • IHC
  • WB
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations