ZFIN ID: ZDB-GENE-020531-2
Gene Name: aryl hydrocarbon receptor 1a
Gene Symbol: ahr1a    Nomenclature History

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Previous Names: ahr1, AHR2 (1), ahra, zfAHR1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have nuclear receptor activity and sequence-specific double-stranded DNA binding activity. Involved in cellular response to organic cyclic compound. Predicted to localize to nucleus. Is expressed in brain; heart; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in retinitis pigmentosa. Orthologous to human AHR (aryl hydrocarbon receptor).
Genome Resources: Alliance (1),  Gene:246224 (1),  Ensembl(GRCz11):ENSDARG00000020046 (1)
GENE EXPRESSION
All Expression Data: 5 figures from 5 publications
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
mu152 Small Deletion Exon 2 Unknown TALEN
mu153 Small Deletion Exon 2 Frameshift, Premature Stop TALEN
mu154 Small Deletion Exon 2 Unknown TALEN
sa1410 Point Mutation Unknown Premature Stop ENU
sa16655 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa28637 Point Mutation Unknown Premature Stop ENU
    uab139 Small Deletion Exon 10 Frameshift, Premature Stop CRISPR
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-ahr1a 1
    MO1-ahr1a N/A 8
    MO2-ahr1a N/A 1
    MO3-ahr1a N/A 1
    TALEN1-ahr1a 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ahr1a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    ?Retinitis pigmentosa 85 618345
    DISEASE ASSOCIATED WITH ahr1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular response to organic cyclic compound (more)
    Cellular Component cytoplasm (more)
    Molecular Function NOT   ligand-activated transcription factor activity (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ahr1a-202 (1)    Ensembl 2759
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ahr1a No data available
    MARKER RELATIONSHIPS
    ahr1a Contained in: [BAC] DKEY-242C17 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131028 (1) 2873 nt
    Genomic GenBank:BX511151 (1) 157538 nt
    Select Tool
    Polypeptide UniProtKB:Q8QGQ3 (1) 805 aa
    Sequence Information (all 13)
    ORTHOLOGY for ahr1a ( Chr: 16 )
    CITATIONS (65)