ZFIN ID: ZDB-GENE-020508-1
Gene Name: crystallin, alpha A
Gene Symbol: cryaa
Sequence Ontology ID : SO:0000704

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Previous Names: [a]A-crystallin (1), hspb4, wu:fc06h04, zgc:92036

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Location: Chr: 1 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 30 figures from 17 publications
Directly Submitted Expression Data: 6 figures (4 images) from Thisse et al., 2004 [MGC:92036]
Wild-type Stages, Structures: Segmentation:10-13 somites (14.0h-16.0h) to Adult (90d-730d, breeding adult)
  head, lens, solid lens vesicle, unspecified (all 5) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la021104Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • vu532 Small Deletion Exon 1 Unknown TALEN
    Targeting reagents: MO1-cryaa (1), MO2-cryaa (1), MO3-cryaa (1), TALEN1-cryaa (1)
    PHENOTYPE
    Data: 3 figures from 2 publications
    Observed in: eye lens, lens, lens development in camera-type eye
    DISEASE ASSOCIATED WITH cryaa HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    cataract 9 multiple types Cataract 9, multiple types 604219
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process eye development (more)
    Molecular Function unfolded protein binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001436 (1)
  • InterPro:IPR002068 (1)
  • InterPro:IPR003090 (1)
  • InterPro:IPR008978 (1)
  • InterPro:IPR012274 (1)
  • InterPro:IPR031107 (1)
  • PROSITE:PS01031 (1)
  • Pfam:PF00011 (1)
  • Pfam:PF00525 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cryaa-001 (1) 1417
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Ab1-cryaa (1)
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM cryaa
    gt(frt-cryaa:egfp-frt,loxp-lox5171-2a-tagrfp-loxp-lox5171), Tg(-0.2unc45b:EGFP,cryaa:mCherry), Tg(-0.4unc45b:EGFP,cryaa:mCherry), Tg(-0.6unc45b:EGFP,cryaa:EGFP), Tg(-0.29unc45b:EGFP,cryaa:mCherry) (all 153) expand
    MARKER RELATIONSHIPS
    cryaaContained in: [BAC] CH211-237A6 (1) (order this)
    cryaaEncodes: [EST] fc06h04
    [cDNA] MGC:92036 (1) (order this), MGC:192061 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_152950 (1) 1430bp
    Genomic GenBank:BX248514 (1) 165693bp
    Select Tool
    Polypeptide UniProtKB:Q8UUZ6 (1) 173aa
    Sequence Clusters UniGene:78315 (1)
    Sequence Information (all 16)
    OTHER cryaa GENE PAGES
  • Alliance (1)
  • Gene:100000769 (1)
  • VEGA:OTTDARG00000019471 (1)
  • Ensembl(GRCz10):ENSDARG00000053502 (1)
  • ORTHOLOGY for cryaa (Chr: 1)
    CITATIONS (132)