Gene

kif11

ID
ZDB-GENE-020426-1
Name
kinesin family member 11
Symbol
kif11 Nomenclature History
Previous Names
  • cb1 (1)
  • chunp6874
  • fa09c03
  • fb23c07
  • kinesin-like protein 1 (1)
  • knsl1 (1)
  • sb:cb1 (1)
  • wu:fa09c03
  • wu:fb23c07
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to have ATP-dependent microtubule motor activity, plus-end-directed. Involved in angiogenesis; neurogenesis; and regulation of cell cycle. Predicted to localize to nucleus and spindle microtubule. Is expressed in blood island; central nervous system; proliferative region; radial glial cell; and trunk. Human ortholog(s) of this gene implicated in microcephaly with or without chorioretinopathy, lymphedema, or mental retardation. Orthologous to human KIF11 (kinesin family member 11).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
11 figures from 6 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kif11 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
microcephaly with or without chorioretinopathy, lymphedema, or mental retardation Alliance Microcephaly with or without chorioretinopathy, lymphedema, or mental retardation 152950
Associated With kif11 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019821 Kinesin motor domain, conserved site
Domain IPR001752 Kinesin motor domain
Domain IPR025901 Kinesin-associated microtubule-binding domain
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036961 Kinesin motor domain superfamily
Domain Details Per Protein
Protein Length Kinesin-associated microtubule-binding domain Kinesin motor domain Kinesin motor domain, conserved site Kinesin motor domain superfamily P-loop containing nucleoside triphosphate hydrolase
UniProtKB:Q8JHI1 955
UniProtKB:F1QK82 1062
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations