ZFIN ID: ZDB-GENE-020419-5
Gene Name: chaperonin containing TCP1, subunit 3 (gamma)
Gene Symbol: cct3    Nomenclature History

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Previous Names: chaperonin containing TCP1, subunit 3, chunp6930, no tectal neuron (1), ntn (1), wu:fb13f04 (1), wu:fb52a02 (1), wu:fj48b06 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have ATP binding activity and unfolded protein binding activity. Involved in embryonic eye morphogenesis and negative regulation of retinal cell programmed cell death. Predicted to localize to chaperonin-containing T-complex. Orthologous to human CCT3 (chaperonin containing TCP1 subunit 3).
Genome Resources: Alliance (1),  Gene:192327 (1),  Ensembl(GRCz11):ENSDARG00000016173 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:64132]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi383aTg Transgenic Insertion Exon 1 Unknown DNA
hi1867Tg Transgenic Insertion Intron 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • jt5 Small Deletion Unknown Frameshift TMP
    sa1761 Point Mutation Unknown Splice Site, Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa28686 Point Mutation Unknown Missense ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-cct3 N/A 1
    DISEASE ASSOCIATED WITH cct3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cct3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process embryonic eye morphogenesis (more)
    Cellular Component cytoplasm (more)
    Molecular Function ATP binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cct3-201 (1)    Ensembl 2129
    ncRNA cct3-002 (1)    Ensembl 566
    cct3-003 (1)    Ensembl 771
    cct3-004 (1)    Ensembl 570
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-cct3 monoclonal IgG1 , k Mouse WB Santa Cruz Biotechnology, Inc.
    2
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cct3
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(-0.6unc45b:cct3-EGFP,cryaa:mCherry) cryaaunc45b cct3EGFPmCherry Danio rerio 1 1
    MARKER RELATIONSHIPS
    cct3 Contained in: [BAC] DKEY-181C1 (1) (order this)
    cct3 Encodes: [EST] fb13f04 (1), fb52a02 (1), fj48b06 (1)
    [STS] chunp6930
    [cDNA] MGC:64132 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_173250 (1) 1981 nt
    Genomic GenBank:CR848742 (1) 177769 nt
    Select Tool
    Polypeptide UniProtKB:Q7T2P2 (1) 543 aa
    Sequence Information (all 18)
    ORTHOLOGY for cct3 ( Chr: 16 )
    CITATIONS (39)