Gene

mcm3

ID
ZDB-GENE-020419-4
Name
minichromosome maintenance complex component 3
Symbol
mcm3 Nomenclature History
Previous Names
  • MCM3z (1)
  • cb32 (1)
  • chunp6867
  • MCM3 minichromosome maintenance deficient 3
  • wu:fa26g03
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Exhibits chromatin binding activity. Involved in retina development in camera-type eye. Predicted to localize to MCM complex and nucleus. Is expressed in several structures, including alar plate midbrain region; blood; immature eye; nervous system; and pectoral fin musculature. Orthologous to human MCM3 (minichromosome maintenance complex component 3).
Genome Resources
Note
None
Expression
All Expression Data
14 figures from 4 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mcm3 Human Ortholog
No data available
Associated With mcm3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018525 Mini-chromosome maintenance, conserved site
Domain IPR001208 MCM domain
Domain IPR003593 AAA+ ATPase domain
Domain IPR027925 MCM N-terminal domain
Domain IPR033762 MCM OB domain
Domain IPR041562 MCM, AAA-lid domain
Family IPR008046 DNA replication licensing factor Mcm3
Family IPR031327 Mini-chromosome maintenance protein
Homologous_superfamily IPR012340 Nucleic acid-binding, OB-fold
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length AAA+ ATPase domain DNA replication licensing factor Mcm3 MCM, AAA-lid domain MCM domain MCM N-terminal domain MCM OB domain Mini-chromosome maintenance, conserved site Mini-chromosome maintenance protein Nucleic acid-binding, OB-fold P-loop containing nucleoside triphosphate hydrolase
UniProtKB:Q5RIC5 807
UniProtKB:Q8JHI8 201
UniProtKB:Q6PH47 807
UniProtKB:A0A0E4AY38 807
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-mcm3 polyclonal IgG Rabbit
  • WB
Bethyl Laboratories, Inc.
3
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations