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ZIRC
ZFIN ID: ZDB-GENE-020419-33
Gene Name: VPS18 core subunit of CORVET and HOPS complexes
Gene Symbol: vps18
Sequence Ontology ID : SO:0000704

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Previous Names: chunp6929, hm:zehl0587, wu:fj35h10 (1)

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(Including Attributions)
Location: Chr: 20 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have protein binding activity, bridging. Involved in several processes, including apical protein localization; endosome to pigment granule transport; and notochord cell vacuolation.  ...
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:103535]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi2499aTg Transgenic Insertion Exon 4 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10171 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH vps18 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH vps18 VIA EXPERIMENTAL MODELS
    Human Disease Fish Conditions Citations
    cholestasis vps18hi2499aTg standard conditions Sadler et al., 2005
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process apical protein localization (more)
    Cellular Component endosome (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 25)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA vps18-201 (1) 3544
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM vps18 No data available
    MARKER RELATIONSHIPS
    vps18Contained in: [BAC] CH211-244P18 (1) (order this), DKEY-14A13 (1) (order this)
    vps18Encodes: [EST] fj35h10 (1), zehl0587 (1)
    [STS] chunp6929
    [cDNA] MGC:103535 (1) (order this), MGC:173734 (1) (order this), MGC:198447 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_173245 (1) 3542bp
    Genomic GenBank:AL929049 (1) 223182bp Blast at MegaBLAST
    Polypeptide UniProtKB:A8WGL1 (1) 974aa
    Sequence Clusters UniGene:8966 (1)
    Sequence Information (all 31)
    ORTHOLOGY for vps18 (Chr: 20)
    CITATIONS (41)