ZFIN ID: ZDB-GENE-020111-3
Gene Name: CCAAT enhancer binding protein beta
Gene Symbol: cebpb    Nomenclature History

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Previous Names: c/ebpb (1), cb380 (1), fe11e05, wu:fe11e05 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have DNA binding activity and DNA-binding transcription factor activity. Involved in regulation of DNA methylation; response to bacterium; and response to yeast. Predicted to localize to nucleus. Is expressed in several structures, including EVL; digestive system; macrophage; periderm; and yolk syncytial layer. Orthologous to human CEBPB (CCAAT enhancer binding protein beta).
Genome Resources: Alliance (1),  Gene:140814 (1),  Ensembl(GRCz11):ENSDARG00000042725 (2)
GENE EXPRESSION
All Expression Data: 40 figures from 21 publications
Directly Submitted Expression Data: 6 figures (10 images) from Thisse et al., 2001 [cb380]
  10 figures (27 images) from Rauch et al., 2003 [fq25d09]
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa14362 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34427 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-cebpb
    1
    CRISPR2-cebpb
    1
    MO1-cebpb N/A 6
    PHENOTYPE
    Data: Fig. 5 from Park et al., 2018
    Observed in:
    DISEASE ASSOCIATED WITH cebpb HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cebpb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to bacterium (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    Browsers: NCBI
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cebpb No data available
    MARKER RELATIONSHIPS
    cebpb Contained in: [BAC] DKEYP-53E12 (1)
    cebpb Encodes: [EST] cb380 (1), fe11e05 (1), fq25d09 (1) (order this)
    [cDNA] MGC:55246 (1), MGC:77577 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131884 (1) 1618 nt
    Genomic GenBank:BX322655 184723 nt
    Select Tool
    Polypeptide UniProtKB:Q7ZU07 (1) 280 aa
    Sequence Information (all 21)
    ORTHOLOGY for cebpb ( Chr: 8 )
    CITATIONS (76)