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ZIRC
ZFIN ID: ZDB-GENE-010803-2
Gene Name: sprouty homolog 4 (Drosophila)
Gene Symbol: spry4
Sequence Ontology ID : SO:0001217

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Previous Names: zSpry4 (1), cb511 (1), sprouty4 (1), wu:fb92b06 (1)

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(Including Attributions)
Location: Chr: 21 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Involved in animal organ development and negative regulation of fibroblast growth factor receptor signaling pathway. Predicted to localize to the cytosol. Human ortholog(s) of this gene implicated in  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fh117 Point Mutation Unknown Premature Stop ENU
  • China Zebrafish Resource Center (CZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la011003Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • spry4_unrecovered Point Mutation Unknown Unknown ENU
    Targeting reagents:
    DISEASE ASSOCIATED WITH spry4 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    hypogonadotropic hypogonadism 17 with or without anosmia Hypogonadotropic hypogonadism 17 with or without anosmia 615266
    DISEASE ASSOCIATED WITH spry4 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process hemopoiesis (more)
    Cellular Component membrane (more)
    Molecular Function molecular_function (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR007875 (1)
  • InterPro:IPR030790 (1)
  • PROSITE:PS51227 (1)
  • Pfam:PF05210 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM spry4 No data available
    MARKER RELATIONSHIPS
    spry4 Contains: [SNP] rs3729148 (1), rs3729149 (1), rs3729150 (1)
    spry4 Encodes: [EST] cb511 (2) (order this), fb92b06 (1), fc35e06 (1)
    [cDNA] MGC:92545 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131826 (1) 2890 bp
    Genomic GenBank:CABZ01085217 (1) 16264 bp
    Polypeptide UniProtKB:F1QZW4 (1) 310 aa
    Sequence Clusters UniGene:32057 (1)
    Sequence Information (all 20)
    OTHER spry4 GENE PAGES
  • Alliance (1)
  • Gene:114437 (1)
  • Ensembl(GRCz11):ENSDARG00000068732 (2)
  • ORTHOLOGY for spry4 ( Chr: 21 )
    CITATIONS (119)