ZFIN ID: ZDB-GENE-010803-2
Gene Name: sprouty homolog 4 (Drosophila)
Gene Symbol: spry4
Sequence Ontology ID : SO:0000704

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Previous Names: zSpry4 (1), cb511 (1), sprouty4 (1), wu:fb92b06 (1)

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(Including Attributions)
Location: Chr: 21 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 46 figures from 35 publications
Directly Submitted Expression Data: 7 figures (49 images) from Thisse et al., 2001 [cb511]
Wild-type Stages, Structures: Blastula:Sphere (4.0h-4.33h) to Adult (90d-730d, breeding adult)
  adaxial cell, brain, caudal fin, central nervous system (all 56) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fh117 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • China Zebrafish Resource Center (CZRC, ZKO consortium) (order this)
  • la011003Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • spry4_unrecovered Point Mutation Unknown Unknown ENU
    Targeting reagents: MO1-spry4 (1), MO2-spry4 (1), MO3-spry4 (1)
    PHENOTYPE
    Data: 5 figures from 3 publications
    Observed in: blood cell, blood circulation, blood vessel remodeling, common cardinal vein (all 13) expand
    DISEASE ASSOCIATED WITH spry4 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    hypogonadotropic hypogonadism 17 with or without anosmia Hypogonadotropic hypogonadism 17 with or without anosmia 615266
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process hemopoiesis (more)
    Cellular Component membrane (more)
    Molecular Function molecular_function (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR007875 (1)
  • InterPro:IPR030790 (1)
  • PROSITE:PS51227 (1)
  • Pfam:PF05210 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM spry4 No data available
    MARKER RELATIONSHIPS
    spry4Contains: [SNP] rs3729148 (1), rs3729149 (1), rs3729150 (1)
    spry4Encodes: [EST] cb511 (2) (order this), fb92b06 (1), fc35e06 (1)
    [cDNA] MGC:92545 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131826 (1) 2890bp
    Genomic GenBank:CABZ01085217 (1) 16264bp
    Polypeptide UniProtKB:F1QZW4 (1) 310aa
    Sequence Clusters UniGene:32057 (1)
    Sequence Information (all 20)
    OTHER spry4 GENE PAGES
  • Alliance (1)
  • Gene:114437 (1)
  • Ensembl(GRCz10):ENSDARG00000068732 (1)
  • ORTHOLOGY for spry4 (Chr: 21)
    CITATIONS (105)