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ZIRC
ZFIN ID: ZDB-GENE-010724-18
Gene Name: apolipoprotein Ea
Gene Symbol: apoea
Sequence Ontology ID : SO:0000704

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Previous Names: ApoE-1 (1), im:7036787, wu:fb69a05, zgc:110064

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(Including Attributions)
Location: Chr: 19 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have several functions, including cholesterol binding activity; cholesterol transfer activity; and phosphatidylcholine-sterol O-acyltransferase activator activity. Predicted to be  ...
GENE EXPRESSION
All Expression Data: 12 figures from 5 publications
Directly Submitted Expression Data: 6 figures (5 images) from Thisse et al., 2004 [MGC:110064]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa36796 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: Fig. S4 from Hwang et al., 2013
    Observed in:
    DISEASE ASSOCIATED WITH apoea HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    age related macular degeneration 1 {?Macular degeneration, age-related} 603075
    Alzheimer's disease 2 Alzheimer disease-2 104310
    hyperlipoproteinemia type III Hyperlipoproteinemia, type III 617347
    {Coronary artery disease, severe, susceptibility to} 617347
    sea-blue histiocytosis Sea-blue histiocyte disease 269600
    Lipoprotein glomerulopathy 611771
    DISEASE ASSOCIATED WITH apoea VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process lipid transport (more)
    Cellular Component extracellular region (more)
    Molecular Function lipid binding (more)
    GO Terms (all 35)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000074 (1)
  • Pfam:PF01442 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA apoea-201 (1) 781
    apoea-202 (1) 1065
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM apoea No data available
    MARKER RELATIONSHIPS
    apoeaContained in: [BAC] CH73-347E22 (1) (order this)
    apoeaContains: [SNP] rs3728965 (1), rs3728966 (1), rs3728967 (1), rs3728968 (1)
    apoeaEncodes: [EST] fb69a05 (1), IMAGE:7036787
    [cDNA] MGC:110064 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001020565 (1) 1086bp
    Genomic GenBank:CU855694 (1) 104180bp
    Select Tool
    Polypeptide UniProtKB:Q503V2 (1) 269aa
    Sequence Clusters UniGene:77157 (1)
    Sequence Information (all 13)
    ORTHOLOGY for apoea (Chr: 19)
    CITATIONS (46)