ZFIN ID: ZDB-GENE-010605-4
Gene Name: v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Bb
Gene Symbol: mafbb    Nomenclature History

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Previous Names: SMaf2 (1), krml2.2, krml2, Zkrml2 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Exhibits sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to localize to nucleus. Is expressed in several structures, including immune system; mesoderm; nervous system; pleuroperitoneal region; and vein. Human ortholog(s) of this gene implicated in Duane retraction syndrome and multicentric carpotarsal osteolysis syndrome. Orthologous to human MAFB (MAF bZIP transcription factor B).
Genome Resources: Alliance (1),  Gene:114463 (1),  Ensembl(GRCz11):ENSDARG00000070542 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa7349 Point Mutation Unknown Missense ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH mafbb HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
multicentric carpotarsal osteolysis syndrome Alliance Multicentric carpotarsal osteolysis syndrome 166300
Duane retraction syndrome 3 617041
DISEASE ASSOCIATED WITH mafbb VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of transcription, DNA-templated (more)
Cellular Component host cell nucleus (more)
Molecular Function sequence-specific DNA binding (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA mafbb-201 (1)    Ensembl 1612
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM mafbb No data available
MARKER RELATIONSHIPS
mafbb Contained in: [BAC] DKEYP-97E7 (1)
mafbb Encodes: [EST] eu239 (1)
[cDNA] MGC:77569 (1), MGC:114026 (1), MGC:191517 (1), MGC:193775 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_131842 (1) 1610 nt
Genomic GenBank:CR932000 (1) 77992 nt
Select Tool
Polypeptide UniProtKB:B3DGW9 (1) 318 aa
Sequence Information (all 29)
ORTHOLOGY for mafbb ( Chr: 11 )
CITATIONS (30)