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ZIRC
ZFIN ID: ZDB-GENE-010601-1
Gene Name: valyl-tRNA synthetase 1
Gene Symbol: vars1
Sequence Ontology ID : SO:0001217

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Previous Names: vars2 (1), vars, CHUNP6879, im:7137378, wu:fb07a11 (1), wu:fb07d10 (1)

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(Including Attributions)
Location: Chr: 16 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have valine-tRNA ligase activity. Predicted to be involved in valyl-tRNA aminoacylation. Predicted to localize to the cytosol. Is expressed in brain; digestive system; immature eye;  ...
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7137378]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi558Tg Transgenic Insertion Intron 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la027672Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • lv101 Small Deletion Unknown Unknown CRISPR
    sa22767 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42669 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44838 Point Mutation Unknown Unknown ENU
    Targeting reagents:
    DISEASE ASSOCIATED WITH vars1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Neurodevelopmental disorder with microcephaly, seizures, and cortical atrophy 617802
    DISEASE ASSOCIATED WITH vars1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process translation (more)
    Cellular Component cytoplasm (more)
    Molecular Function aminoacyl-tRNA editing activity (more)
    GO Terms (all 11)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA vars-201 (1) 4150
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM vars1 No data available
    MARKER RELATIONSHIPS
    vars1 Contained in: [BAC] CH73-54F23 (1) (order this)
    vars1 Encodes: [BAC END] zk18d13.sp6
    [EST] fb07a11 (1), fb07d10 (1), IMAGE:7137378 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001311346 (1)
    Genomic GenBank:CU929328 (1) 119013 bp
    Select Tool
    Polypeptide UniProtKB:F1Q740 (1) 1271 aa
    Sequence Clusters UniGene:1481 (1)
    Sequence Information (all 24)
    ORTHOLOGY for vars1 ( Chr: 16 )
    CITATIONS (38)