Gene

ucp1

ID
ZDB-GENE-010503-1
Name
uncoupling protein 1
Symbol
ucp1 Nomenclature History
Previous Names
  • ucp4
  • UCPx (1)
  • fb62c08
  • wu:fb62c08
  • zUCPx (1)
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to enable oxidative phosphorylation uncoupler activity. Acts upstream of or within cellular response to estrogen stimulus. Predicted to be located in mitochondrial membrane. Predicted to be integral component of membrane. Is expressed in several structures, including brain; heart; liver; median fin fold; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in hypertension and type 2 diabetes mellitus. Orthologous to human UCP1 (uncoupling protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ucp1 Human Ortholog
No data available
Associated With ucp1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR002030 Mitochondrial carrier UCP-like
Family IPR040011 Mitochondrial brown fat uncoupling protein 1
Homologous_superfamily IPR023395 Mitochondrial carrier domain superfamily
Repeat IPR018108 Mitochondrial substrate/solute carrier
Domain Details Per Protein
Protein Length Mitochondrial brown fat uncoupling protein 1 Mitochondrial carrier domain superfamily Mitochondrial carrier UCP-like Mitochondrial substrate/solute carrier
UniProtKB:Q7ZVP4 309
UniProtKB:Q6TGS8 309
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations