Gene

skiv2l

ID
ZDB-GENE-010430-5
Name
SKI2 homolog, superkiller viralicidic activity 2-like
Symbol
skiv2l Nomenclature History
Previous Names
  • fb70b07
  • wu:fb70b07
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have RNA helicase activity. Predicted to be involved in nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay. Predicted to localize to Ski complex. Human ortholog(s) of this gene implicated in trichohepatoenteric syndrome 2. Orthologous to human SKIV2L (Ski2 like RNA helicase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With skiv2l Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
trichohepatoenteric syndrome 2 Alliance Trichohepatoenteric syndrome 2 614602
Associated With skiv2l Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001650 Helicase, C-terminal
Domain IPR011545 DEAD/DEAH box helicase domain
Domain IPR012961 ATP-dependent RNA helicase Ski2, C-terminal
Domain IPR014001 Helicase superfamily 1/2, ATP-binding domain
Domain IPR025696 rRNA-processing arch domain
Domain IPR040801 Ski2, N-terminal domain
Family IPR016438 ATP-dependent RNA helicase Ski2-like
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length ATP-dependent RNA helicase Ski2, C-terminal ATP-dependent RNA helicase Ski2-like DEAD/DEAH box helicase domain Helicase, C-terminal Helicase superfamily 1/2, ATP-binding domain P-loop containing nucleoside triphosphate hydrolase rRNA-processing arch domain Ski2, N-terminal domain
UniProtKB:B7ZUW9 1249
UniProtKB:Q1LWQ1 1230
UniProtKB:F1R881 1249
UniProtKB:A0A2R8Q6L8 1277
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations