ZFIN ID: ZDB-GENE-010430-5
Gene Name: SKI2 homolog, superkiller viralicidic activity 2-like
Gene Symbol: skiv2l    Nomenclature History

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Previous Names: fb70b07, wu:fb70b07

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have RNA helicase activity. Predicted to be involved in nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay. Predicted to localize to the Ski complex. Orthologous to human SKIV2L (Ski2 like RNA helicase).
Genome Resources: Alliance (1),  Gene:559653 (1),  Ensembl(GRCz11):ENSDARG00000062206 (2)
GENE EXPRESSION
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH skiv2l HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
trichohepatoenteric syndrome 2 Alliance Trichohepatoenteric syndrome 2 614602
DISEASE ASSOCIATED WITH skiv2l VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process RNA catabolic process (more)
Cellular Component Ski complex (more)
Molecular Function ATP binding (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR001650 Helicase, C-terminal
Domain IPR011545 DEAD/DEAH box helicase domain
Domain IPR012961 ATP-dependent RNA helicase Ski2, C-terminal
Domain IPR014001 Helicase superfamily 1/2, ATP-binding domain
Family IPR016438 ATP-dependent RNA helicase Ski2-like
Domain IPR025696 rRNA-processing arch domain
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain IPR040801 Ski2, N-terminal domain
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA skiv2l-201 (1)    Ensembl 4191
ncRNA ottdart00000045245 (1)    Ensembl 789
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM skiv2l No data available
MARKER RELATIONSHIPS
skiv2l Contained in: [BAC] CH73-276C21 (1), CH211-222E23 (1)
[Fosmid] CH1073-396A17 (1)
skiv2l Encodes: [EST] fb70b07
[cDNA] MGC:198104 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001044901 (1) 3704 bp
Genomic GenBank:BX537337 217375 bp Blast at MegaBLAST
Polypeptide UniProtKB:A0A2R8Q6L8 (1) 1277 aa
Sequence Information (all 19)
ORTHOLOGY for skiv2l ( Chr: 19 )
CITATIONS (22)