Gene

skiv2l

ID

ZDB-GENE-010430-5

Name

SKI2 homolog, superkiller viralicidic activity 2-like

Symbol

skiv2l Nomenclature History

Previous Names

fb70b07
wu:fb70b07

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to have RNA helicase activity. Predicted to be involved in nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay. Predicted to localize to Ski complex. Human ortholog(s) of this gene implicated in trichohepatoenteric syndrome 2. Orthologous to human SKIV2L (Ski2 like RNA helicase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

Thisse Expression Data

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With skiv2l Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
trichohepatoenteric syndrome 2	Alliance	Trichohepatoenteric syndrome 2	614602

Associated With skiv2l Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001650	Helicase, C-terminal
Domain	IPR011545	DEAD/DEAH box helicase domain
Domain	IPR012961	ATP-dependent RNA helicase Ski2, C-terminal
Domain	IPR014001	Helicase superfamily 1/2, ATP-binding domain
Domain	IPR025696	rRNA-processing arch domain
Domain	IPR040801	Ski2, N-terminal domain
Family	IPR016438	ATP-dependent RNA helicase Ski2-like
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase

Domain Details Per Protein

Protein	Length	ATP-dependent RNA helicase Ski2, C-terminal	ATP-dependent RNA helicase Ski2-like	DEAD/DEAH box helicase domain	Helicase, C-terminal	Helicase superfamily 1/2, ATP-binding domain	P-loop containing nucleoside triphosphate hydrolase	rRNA-processing arch domain	Ski2, N-terminal domain
UniProtKB:B7ZUW9 InterPro	1249
UniProtKB:Q1LWQ1 InterPro	1230
UniProtKB:F1R881 InterPro	1249
UniProtKB:A0A2R8Q6L8 InterPro	1277

Transcripts

Genome Browsers

Type	Name	Length (nt)	Analysis
mRNA	skiv2l-201 (1) Ensembl	4191 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	ottdart00000045245 (1) Ensembl	789 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations