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ZIRC
ZFIN ID: ZDB-GENE-010403-1
Gene Name: cone-rod homeobox
Gene Symbol: crx
Sequence Ontology ID : SO:0000704

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
AUTOMATED DESCRIPTION
Exhibits DNA binding activity. Involved in eye photoreceptor cell development; negative regulation of retinal cell programmed cell death; and visual perception. Predicted to localize to the nucleus.  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents:
DISEASE ASSOCIATED WITH crx HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
cone-rod dystrophy 2 Cone-rod retinal dystrophy-2 120970
Leber congenital amaurosis 7 Leber congenital amaurosis 7 613829
DISEASE ASSOCIATED WITH crx VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process eye development (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 11)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA crx-201 (1) 2381
antisense ottdart00000059965 (1) 825
GENE PRODUCT DESCRIPTION
INTERACTIONS AND PATHWAYS
ANTIBODIES
PLASMIDSNo data available
MARKER RELATIONSHIPS
crxContained in: [BAC] CH211-46E8 (1) (order this)
crxEncodes: [EST] eu16 (1), eu68 (1)
[cDNA] MGC:73334 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_152940 (1) 2385bp
Genomic GenBank:BX927323 119560bp
Select Tool
Polypeptide UniProtKB:Q8JIZ3 (1) 281aa
Sequence Clusters UniGene:14325 (1)
Sequence Information (all 14)
ORTHOLOGY for crx (Chr: 5)
CITATIONS (94)