Gene
gfra1b
- ID
- ZDB-GENE-010226-3
- Name
- gdnf family receptor alpha 1b
- Symbol
- gfra1b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have signaling receptor activity. Involved in enteric nervous system development. Predicted to localize to external side of plasma membrane and receptor complex. Is expressed in nervous system; presumptive enteric nervous system; pronephric duct; and vagal neural crest. Orthologous to human GFRA1 (GDNF family receptor alpha 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Renal hypodysplasia/aplasia 4 | 619887 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GDNF/GAS1 | GDNF receptor alpha | Glial cell line-derived neurotrophic factor receptor | Glial cell line-derived neurotrophic factor receptor, alpha 1/2 |
|---|---|---|---|---|---|
|
UniProtKB:Q98TT8
|
481 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
gfra1b-201
(1)
|
Havana | 1556 nt | |
| ncRNA |
gfra1b-002
(1)
|
Havana | 535 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-gfra1 | polyclonal | Rabbit |
|
Santa Cruz Biotechnology, Inc.
|
3 |
Plasmids
No data available