ZFIN ID: ZDB-GENE-010131-2
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Gene Name: cyclin-dependent kinase 5
Gene Symbol: cdk5
Sequence Ontology ID : SO:0000704

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Previous Name: zgc:101604

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Location: Chr: 24 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits cyclin-dependent protein serine/threonine kinase activity and histone kinase activity; involved in several processes, including animal organ development, negative regulation of neuron  ...
GENE EXPRESSION
All Expression Data: 7 figures from 7 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:101604]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ki110 Small Deletion Unknown Frameshift, Premature Stop CRISPR
la014588Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • la023006Tg Transgenic Insertion Unknown Unknown DNA
    la023007Tg Transgenic Insertion Unknown Unknown DNA
    la023008Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • Targeting reagents:
    PHENOTYPE
    Data: 8 figures from 4 publications
    Observed in:
    DISEASE ASSOCIATED WITH cdk5 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    ?Lissencephaly 7 with cerebellar hypoplasia 616342
    DISEASE ASSOCIATED WITH cdk5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of neuron apoptotic process (more)
    Cellular Component cytosol (more)
    Molecular Function histone kinase activity (more)
    GO Terms (all 22)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000719 (1)
  • InterPro:IPR008271 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR017441 (1)
    		•
  • PROSITE:PS00107 (1)
  • PROSITE:PS00108 (1)
  • PROSITE:PS50011 (1)
    		•
  • Pfam:PF00069 (1)
    		•
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cdk5-001 (1) 1899
    Select Tool
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM cdk5 No data available
    MARKER RELATIONSHIPS
    cdk5Contained in: [BAC] DKEYP-87A6 (1)
    cdk5Encodes: [cDNA] MGC:101604 (1) (order this), MGC:191976 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131719 (1) 2881bp
    Select Tool
    Genomic GenBank:CU019563 (1) 194521bp
    Select Tool
    Polypeptide UniProtKB:Q5U3V4 (1) 292aa
    Select Tool
    Sequence Clusters UniGene:105878 (1)
    Sequence Information (all 17)
    OTHER cdk5 GENE PAGES
  • Alliance (1)
  • Gene:65234 (1)
  • VEGA:OTTDARG00000032053 (1)
  • Ensembl(GRCz11):ENSDARG00000056683 (2)
    • ORTHOLOGY for cdk5 (Chr: 24)
    CITATIONS (37)