ZFIN ID: ZDB-GENE-010131-2
Gene Name: cyclin-dependent kinase 5
Gene Symbol: cdk5
Sequence Ontology ID : SO:0000704

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Previous Name: zgc:101604

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Location: Chr: 24 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 7 figures from 7 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:101604]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
  blastomere, brain, central nervous system, immature eye (all 9) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la014588Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la023006Tg Transgenic Insertion Unknown Unknown DNA
    la023007Tg Transgenic Insertion Unknown Unknown DNA
    la023008Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-cdk5 (1), MO2-cdk5 (1), MO3-cdk5 (1)
    PHENOTYPE
    Data: 7 figures from 3 publications
    Observed in: brain motor neuron, cranial nerve II, cyclin-dependent protein serine/threonine kinase activity, eye (all 15) expand
    DISEASE ASSOCIATED WITH cdk5 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    ?Lissencephaly 7 with cerebellar hypoplasia 616342
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of neuron apoptotic process (more)
    Cellular Component cytosol (more)
    Molecular Function histone kinase activity (more)
    GO Terms (all 21)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000719 (1)
  • InterPro:IPR008271 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR017441 (1)
  • PROSITE:PS00107 (1)
  • PROSITE:PS00108 (1)
  • PROSITE:PS50011 (1)
  • Pfam:PF00069 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cdk5-001 (1) 1899
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Ab1-cdk5 (1)
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM cdk5 No data available
    MARKER RELATIONSHIPS
    cdk5Contained in: [BAC] DKEYP-87A6 (1)
    cdk5Encodes: [cDNA] MGC:101604 (1) (order this), MGC:191976 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131719 (1) 2881bp
    Genomic GenBank:CU019563 (1) 194521bp
    Select Tool
    Polypeptide UniProtKB:F6NUS5 (1) 299aa
    Sequence Clusters UniGene:105878 (1)
    Sequence Information (all 18)
    OTHER cdk5 GENE PAGES
  • Alliance (1)
  • Gene:65234 (1)
  • VEGA:OTTDARG00000032053 (1)
  • Ensembl(GRCz10):ENSDARG00000056683 (1)
  • ORTHOLOGY for cdk5 (Chr: 24)
    CITATIONS (33)