Gene

klf17

ID
ZDB-GENE-010129-1
Name
Kruppel-like factor 17
Symbol
klf17 Nomenclature History
Previous Names
  • klf4
  • klf4b (1)
  • biklf
  • blood island-enriched Kruppel-like factor
  • etID46628.2 (1)
  • id:ibd5109
  • ik:tdsubc_1b8 (1)
  • ik:tdsubc_1e12
  • ik:tdsubc_1e5
  • wu:fc09b11 (1)
  • xx:tdsubc_1b8
  • xx:tdsubc_1e12
  • xx:tdsubc_1e5
  • zgc:109839
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Exhibits DNA binding activity. Involved in several processes, including erythrocyte differentiation; hatching gland development; and regulation of gene expression. Predicted to localize to nucleus. Is expressed in several structures, including ectoderm; germ ring; hematopoietic system; lateral line system; and mesoderm. Orthologous to several human genes including KLF2 (Kruppel like factor 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
35 figures from 23 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
12 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With klf17 Human Ortholog
No data available
Associated With klf17 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013087 Zinc finger C2H2-type
Homologous_superfamily IPR036236 Zinc finger C2H2 superfamily
Domain Details Per Protein
Protein Length Zinc finger C2H2 superfamily Zinc finger C2H2-type
UniProtKB:Q9DFS2 409
UniProtKB:Q90XE8 408
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Note
Oates et al. (2001) ZDB-PUB-010912-8 originally classified this gene as an orthologue of mammalian KLF4, based on amino acid sequence homology. A more complete analysis in Kotkamp et al. (2014) ZDB-PUB-131218-14 presented synteny evidence supporting orthology to mammalian KLF17 genes.
Citations