ZFIN ID: ZDB-GENE-010126-3
Gene Name: neurotrophic tyrosine kinase, receptor, type 3a
Gene Symbol: ntrk3a    Nomenclature History

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Previous Names: trkC1 (1), si:ch73-236b16.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to have neurotrophin binding activity; neurotrophin receptor activity; and transmembrane receptor protein tyrosine kinase activity. Involved in central nervous system development and negative regulation of apoptotic process. Predicted to localize to axon; integral component of plasma membrane; and receptor complex. Is expressed in nervous system and otic vesicle. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human NTRK3 (neurotrophic receptor tyrosine kinase 3).
Genome Resources: Alliance (1),  Gene:568668 (1),  Ensembl(GRCz11):ENSDARG00000077228 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la010339Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la023126Tg Transgenic Insertion Unknown Unknown DNA
    sa13864 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24620 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa30214 Point Mutation Unknown Premature Stop ENU
    sa38018 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38019 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ntrk3a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ntrk3a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process central nervous system development (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 29)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ntrk3a-202 (1)    Ensembl 13332
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ntrk3a No data available
    MARKER RELATIONSHIPS
    ntrk3a Contained in: [BAC] CH73-309L7 (1), CH211-256N6 (1), DKEY-18E5 (1) (order this), DKEYP-92C6 (1)
    ntrk3a Encodes: [STS] zfish44910-890h03.q1k
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001256664 (1) 3475 nt
    Genomic RefSeq:NW_018395189 (1) Blast at MegaBLAST
    Polypeptide UniProtKB:A0A0R4ITE7 (1) 821 aa
    Sequence Information (all 20)
    ORTHOLOGY for ntrk3a ( Chr: 25 )
    CITATIONS (40)